基于嵌入式的食管起搏系统的研究与设计

发布时间：2018-04-09 00:22

本文选题：功能性电刺激　切入点：多通道　出处：《天津大学》2016年硕士论文

【摘要】：贲门失弛缓症(achalasia)是一种食管运动障碍性疾病,多发病于20-50岁年龄段人群。该病的主要特征是食管下括约肌(low esophageal sphincter,LES)松弛障碍、吞咽时食管体部缺乏蠕动性收缩,临床上表现为不同程度的吞咽困难、疼痛、食物反流等症状,严重影响病人生活质量。针对贲门失弛缓症的治疗需求,本文设计了基于多通道电刺激的食管起搏系统。系统以低功耗单片机MSP430为核心处理器,利用前端脉冲发生信号控制低功率压控精密恒流电路,并采用软件精确延时等技术,实现了刺激脉冲的生成、多通道顺序输出、脉冲参数可调等功能。本文完成的主要工作如下:1.设计了基于嵌入式的食管起搏系统方案,完成功能模块划分。2.完成了吞咽信号的采集与处理方案,利用吞咽传感器和前端模拟电路生成了符合要求的刺激脉冲启动信号。3.采用低功耗单片机MSP430为核心处理器,设计了刺激发生电路和刺激输出电路,实现了刺激脉冲的产生、多通道顺序输出以及参数的灵活可调。4.设计控制显示模块,实现参数的可控可调节;设计了无线数据传输模块,实现体内和体外模块的通讯。5.搭建食管起搏实验系统,完成系统性能参数的测试实验,验证了系统设计的正确性和可行性。
[Abstract]:Achalasia (achalasia) is an esophageal dyskinesia disease that occurs frequently in the 20-50 age group.The main characteristic of the disease is the relaxation disorder of the lower esophageal sphincter (low esophageal sphincter), the lack of peristaltic contraction in the esophageal body during swallowing, and the clinical manifestations of dysphagia, pain, food reflux and other symptoms, which seriously affect the quality of life of the patients.To meet the need of treatment for achalasia, a multichannel electrical stimulation based esophageal pacing system was designed.The system uses low-power single-chip computer MSP430 as the core processor, uses the front-end pulse generation signal to control the low-power voltage control precision constant current circuit, and adopts the software precise delay technology, realizes the stimulation pulse generation, the multi-channel sequential output, and so on.Pulse parameters can be adjusted, etc.The main work accomplished in this paper is as follows: 1.The esophageal pacing system based on embedded system is designed, and the function module is divided into 2. 2.The sampling and processing scheme of swallowing signal is completed, and the stimulation pulse start signal .3is generated by using swallowing sensor and front-end analog circuit.The stimulation generation circuit and the stimulation output circuit are designed by using the low-power MCU MSP430 as the core processor. The stimulation pulse generation, the multi-channel sequential output and the flexible adjustable .4of the parameters are realized.A control display module is designed to realize the controllable and adjustable parameters, and a wireless data transmission module is designed to realize the communication between in vivo and in vitro modules.The experimental system of esophageal pacing was built, and the test of system performance parameters was completed, which verified the correctness and feasibility of the system design.
【学位授予单位】：天津大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：TH789

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