不同血容量机采血小板献血者筛选条件分析

发布时间：2017-12-31 21:18

本文关键词：不同血容量机采血小板献血者筛选条件分析　出处：《中国输血杂志》2017年07期 　论文类型：期刊论文

【摘要】：目的通过对不同血容量献血者机采血小板产品的聚集情况、血小板含量、机采循环血量等分析,得出不同血容量的机采献血者上机的合适条件。方法随机选取本中心307名合格的机采献血者,通过献血者相关指标研究献血者的循环血量、血容量PBV、性别、采前Plt、HCT、PCT,机采血小板的聚集与采集时间的关系;不同血容量、不同血小板计数分组的机采血小板聚集率的差别;不同血容量分组的血小板收集量,循环血量的比较。使用SPSS17.0统计软件,进行数据分析,分析方法包括多元回归分析、χ~2检验、t检验等。结果 1)采前PLT、PBV、HCT越低,采集时间越长,而性别和PCT与采集时间无关;采集时间越长,机采血小板聚集的可能性越高。2)低血容量组和低血小板计数组,机采血小板聚集率较高。3)机采献血者的血容量越高,其机采血小板的收集量越多,循环血量越少。结论根据不同血容量献血者体检的各项指标,进一步对其进行合理的分析,优化机采方案,尤其对血容量较低的献血者进行合理安排,从而提高血小板采集的质量。
[Abstract]:Objective to analyze the aggregation of platelet products, platelet content and circulating blood volume of blood donors of different blood volume. Methods 307 qualified blood donors were randomly selected to study the circulating blood volume (PBV) and blood volume (PBV) of blood donors. Sex, the relationship between platelet aggregation and collecting time; The difference of platelet aggregation rate between different blood volume and different platelet count groups; The platelet collection and circulating blood volume in different blood volume groups were compared. The data were analyzed by SPSS17.0 software. The analysis methods included multiple regression analysis and 蠂 2 test. Results 1) the lower the pre-harvest PCT, the longer the collection time, but the gender and PCT were not related to the acquisition time. The longer the collection time, the higher the probability of platelet aggregation. 2) the lower the blood volume and the lower the platelet count, the higher the platelet aggregation rate. 3) the higher the blood volume of the donor. The more platelet was collected, the less the circulating blood volume was. Conclusion according to the indexes of physical examination of blood donors of different blood volume, further reasonable analysis is carried out to optimize the mechanical collection scheme. In order to improve the quality of platelet collection, reasonable arrangement was made for blood donors with low blood volume.
【作者单位】：大连市血液中心;
【分类号】：R446.11
【正文快照】： 机采血小板亦称单采血小板,是使用血细胞分离机从单一供体血液中循环一次采集一个治疗量的血小板,并同时将血液中其他成分还输[1]。机采血小板具有含量高,纯度高,输注安全性高,临床治疗效果显著等优点,因而在临床中的应用日益广泛。随着输血技术的飞速发展、血分离技术的进步

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