基于S-G滤波理论的超声造影定量分析技术评估肝肿瘤血流动力学的方法学研究

发布时间：2018-01-01 18:08

本文关键词：基于S-G滤波理论的超声造影定量分析技术评估肝肿瘤血流动力学的方法学研究　出处：《中国超声医学杂志》2017年10期 　论文类型：期刊论文

【摘要】：目的探索基于S-G滤波理论的超声造影(CEUS)定量分析(SGCQ)软件分析肝肿瘤血流动力学的方法和初步结果。方法入选40个肝细胞癌及40个转移性肝肿瘤病灶,造影采用Philips iU 22系统,C5-1探头,频率2~4 MHz,声诺维2.4ml团注。SGCQ软件脱机分析造影数据,获取感兴趣区的灌注参数。比较不同研究者分析结果的一致性;比较肿瘤与肝实质、两种肿瘤病灶之间的参数。结果所有参数组内相关系数0.8。上升斜率a2、下降斜率a3、曲线下面积(AUC)及灌注时间在肝细胞癌及肝实质间有统计学差异。除增强强度外,转移性肝肿瘤与肝实质间各参数有统计学差异。a2、a3、AUC在两种肿瘤间有统计学差异。结论 SGCQ软件定量分析具有良好的重复性,该软件能显示出肝细胞癌及转移性肝肿瘤的血流动力学特点及二者之间的差异。
[Abstract]:Objective to explore the quantitative analysis of SGCQs by contrast-enhanced ultrasound (CEUs) based on S-G filter theory. Methods 40 hepatocellular carcinoma and 40 metastatic liver tumor lesions were selected. The imaging data were analyzed offline by the Philips iU22 system with a C5-1 probe with a frequency of 2 ~ 4 MHz and a 2.4ml group injection of Sonovir with the software of SGCQ. The perfusion parameters of the region of interest were obtained. The consistency of the results of different researchers was compared. The parameters between tumor and hepatic parenchyma were compared. Results the correlation coefficient in all parameter groups was 0.8. The slope of ascending slope was 2, and the slope of descending slope was 3. The area under the curve and perfusion time were significantly different between hepatocellular carcinoma and hepatic parenchyma. Except for the enhancement intensity, the parameters of metastatic liver tumor and hepatic parenchyma were significantly different. AUC was statistically different between the two types of tumor. Conclusion the quantitative analysis of SGCQ software has good reproducibility. The software can show the hemodynamic characteristics of hepatocellular carcinoma and metastatic liver tumor and the difference between them.
【作者单位】：复旦大学附属中山医院超声科;
【分类号】：R445.1;R735.7
【正文快照】： 结果所有参数组内相关系数0.8。上升斜率a2、下降斜率a3、曲线下面积(AUC)及灌注时间在肝细胞癌及肝实质间有统计学差异。除增强强度外,转移性肝肿瘤与肝实质间各参数有统计学差异。a2、a3、AUC在两种肿瘤间有统计学差异。结论SGCQ软件定量分析具有良好的重复性,该软件能显示

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