少见纵隔恶性生殖细胞来源肿瘤的CT诊断

发布时间：2018-01-13 08:26

本文关键词：少见纵隔恶性生殖细胞来源肿瘤的CT诊断　出处：《临床放射学杂志》2017年07期 　论文类型：期刊论文

【摘要】：目的探讨少见纵隔恶性生殖细胞来源肿瘤的CT影像学特征。方法回顾性分析经病理证实的7例少见纵隔恶性生殖细胞来源肿瘤的CT表现。结果 7例肿块均位于前上纵隔,其中精原细胞瘤3例,卵黄囊瘤2例,胚胎性癌1例,混合性生殖细胞肿瘤(90%卵黄囊瘤,10%胚胎性癌)1例。CT表现为圆形或类圆形肿块,肿块内见不同程度囊变或坏死液化区,未见钙化及脂肪成分,边缘不规则与周围脂肪间隙消失并侵犯邻近组织器官等恶性肿瘤征象。3例精原细胞瘤以实性成分为主,强化较均匀,其中1例β-HCG轻度升高;2例卵黄囊瘤以囊性成分为主,实性成分相对少并呈明显不均匀强化,有延迟渐进性强化的特征,AFP显著升高。1例胚胎性癌实性成分呈轻度强化,囊性坏死区无强化。1例混合性生殖细胞肿瘤实性成分呈中度强化,其影像学表现取决于肿块内所含成分及所占比例有关。结论少见纵隔恶性生殖细胞来源肿瘤CT表现具有一定特征性,结合血清AFP及β-HCG有助于提高对该类疾病诊断的准确性。
[Abstract]:Objective to investigate the CT imaging features of rare mediastinal malignant germ cell tumors. Methods Retrospective analysis of CT manifestations of rare mediastinal malignant germ cell tumors confirmed by pathology in 7 cases. Results 7 cases were located in the upper anterior mediastinal tumor, including 3 cases of seminoma, 2 cases of yolk sac tumor, 1 cases of embryonal carcinoma, mixed germ cell tumor (90% yolk sac tumor, embryonal carcinoma 10%) 1 cases of.CT showed round or round mass, different degrees of cystic degeneration or necrosis in the tumor liquefaction area, calcification and fat, irregular edge and fat clearance around the lost and invade the adjacent organs such as.3 signs of malignant tumor cases of seminoma with solid components, strengthening is uniform, including 1 cases of beta -HCG increased slightly; 2 cases of yolk sac tumor cystic and solid component is relatively small and showed obvious heterogeneous enhancement, delayed enhancement of the progressive characteristics of AF. P significantly increased the solid component.1 cases of embryonal carcinoma showed slight enhancement, no enhancement of.1 cases of mixed germ cell tumor of the solid components showed moderate enhancement of cystic necrotic area, the imaging performance depends on the mass contained within the composition and proportion. Conclusion rare mediastinal malignant germ cell tumor with CT source certain characteristics, combined with serum AFP and beta -HCG helps to improve the accuracy of the diagnosis of these diseases.

【作者单位】：贵州省人民医院放射科;
【分类号】：R730.44;R734.5
【正文快照】： 纵隔生殖细胞来源肿瘤在纵隔原发肿瘤中较为少见,病理类型以畸胎瘤居多。畸胎瘤由来自两个或三个胚层的数种成熟和(或)不成熟的体细胞组织构成,瘤体内可见多种组织成分,如脂肪、钙化或骨骼、水及软组织密度;良性畸胎瘤约占纵隔生殖细胞瘤的75%以上,CT诊断较为容易[1]。少见的

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