男性泌尿生殖道支原体感染特征及耐药性分析

发布时间：2018-01-13 12:32

  本文关键词：男性泌尿生殖道支原体感染特征及耐药性分析　出处：《中国病原生物学杂志》2017年07期 　论文类型：期刊论文

  更多相关文章： 男性泌尿生殖道 支原体 临床特征 耐药性

【摘要】：目的了解男性泌尿生殖道支原体感染特征及耐药性,为临床治疗提供指导。方法收集重庆三峡中心医院、湖北医药学院附属人民医院2014~2015年男科就诊的男性患者临床资料,收集精液、尿液、尿道分泌物、前列腺液标本,对标本进行支原体培养检测及耐药性分析。结果 2014-2015年共检测男性患者1 712例,支原体感染570例,感染率33.29%;其中2014年734例,感染211例,感染率28.75%;2015年978例,感染359例,感染率36.71%。≤20岁、21岁~、31岁~、≥41岁人群支原体感染率分别为19.39%、26.92%、50.58%和22.70%。31岁~组感染率与≤20岁、21岁~和≥41岁组比较,差异均有统计学意义(χ~2=73.6888,63.5098,71.3700,P均0.05)。无性伴侣者、有1个、≥2个性伴侣者感染率分别为12.11%(39/322)、28.87%(136/471)和42.98%(395/919);≥2个性伴侣组与无性伴侣组、1个性伴侣组比较,差异均有统计学意义(χ~2=99.9182,26.2493,P均0.05)。共分离出364株支原体,其中UU191株,MH 75株,UU+MH 98株。2014年分离139株,其中UU 73株,MH 29株,UU+MH 37株;2015年分离225株,其中UU 118株,MH 46株,UU+MH 61株。2014年分离的73株和2015年118株UU对TET、ASP、ERY、ROX、DOX、CRA、OFL、MIN、JOX和AZI的耐药率分别为83.56%、36.99%、97.26%、38.36%、8.22%、12.33%、46.58%、16.44%、19.18%、26.03%和79.66%、34.75%、92.37%、40.68%、6.78%、37.29%、55.08%、14.41%、12.71%、38.98%。结论男性泌尿生殖道支原体感染者主要集中于21~40岁的性活跃者,性伴侣较多者感染率也较高。2014-2015年男性泌尿生殖道支原体以UU为主,临床治疗中可优先选用交沙霉素、美满霉素及强力霉素等。
[Abstract]:Objective to understand the characteristics of male genitourinary tract mycoplasma infection and drug resistance, and provide guidance for clinical treatment. Methods the clinical data of male patients, the Central Hospital of Chongqing Three Gorges, Hubei Medical College Affiliated Hospital of 2014~2015 in andrology outpatient collected semen, urine, urinary tract secretions and prostatic fluid samples, detection and drug resistance analysis of mycoplasma culture specimens. Results 2014-2015 there were 1712 cases of male patients, 570 cases of mycoplasma infection, the infection rate was 33.29%; in 2014 734 cases, 211 cases of infection, the infection rate was 28.75%; in 2015 978 cases, 359 Cases of infection, the infection rate of 36.71%. is less than or equal to 20 years old, 21 years old, 31 years old, people aged 41 years or over mycoplasma infection rates were 19.39%, 26.92% the 50.58% year old group, and 22.70%.31 infection rate and less than 20 years old, 21 years old and above 41 years old group were compared, the differences were statistically significant (x ~2=73.6888,63.5098,71.3700, P < 0.05). There are 1 sexual partners, 涓，

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