乙醇封管对导管相关性血流感染预防效果的Meta分析

发布时间：2018-01-14 02:03

本文关键词：乙醇封管对导管相关性血流感染预防效果的Meta分析　出处：《中华医院感染学杂志》2017年18期 　论文类型：期刊论文

【摘要】：目的评价乙醇封管对导管相关性血流感染的预防效果。方法计算机检索PubMed、The Cochrane Library、EMbase、CBM、CNKI数据库从2007年1月至2017年7月的相关文献,纳入乙醇封管用于预防导管相关性血流感染的随机对照试验,由2名研究者独立筛选文献、提取资料和评价纳入研究的方法学质量。结果共纳入9篇文献研究,2443例患者。结果显示,乙醇封管组CRBSI发生率低于对照组[RR=0.57,95%CI(0.39,0.83),P=0.003],而两组在导管出口部位感染、不良反应、血栓和导管功能不良方面没有统计学差异。结论乙醇封管能够减少导管相关性血流感染的发生;受所纳入研究质量的限制,尚需要开展更多高质量研究予以验证。
[Abstract]:Objective to evaluate the effect of alcohol sealing on the prevention of catheter-related blood flow infection. Methods the Cochrane Library EMbase Cochrane was searched by computer. From January 2007 to July 2017, the CNKI database was included in a randomized controlled trial of alcohol capping for the prevention of catheter-related blood flow infection. The literature was independently screened by two researchers. Results two hundred and forty-three patients were included in 9 literature studies. The results showed that the incidence of CRBSI in the ethanol sealed group was lower than that in the control group. [RRN 0.57 ~ 95CII 0.39 ~ 0.83% P0. 003, while the two groups were infected at the outlet of the catheter and had adverse reactions. There was no statistical difference between thrombus and ductal dysfunction. Conclusion Alcohol sealing can reduce the incidence of catheter-related blood flow infection. Limited by the quality of the research included, more high-quality studies are needed to verify it.
【作者单位】：四川大学华西医院医院感染管理部;四川大学华西临床医学院护理系;
【分类号】：R473
【正文快照】： 中心静脉导管在用于抢救危重患者的同时,也易导致患者发生局部或全身并发症,如导管出口部位感染和导管相关性血流感染(CRBSI)。据美国CDC报道,尽管2008-2013年间美国的导管相关血流感染率下降了46%,但仍然每年大约有30100例中心静脉导管相关性血流感染在医院发生。CRBSI的发生

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