基于MRI常规序列信号、强化程度以及ADC值鉴别不同亚型脑膜瘤

发布时间：2018-01-15 06:16

本文关键词：基于MRI常规序列信号、强化程度以及ADC值鉴别不同亚型脑膜瘤　出处：《临床放射学杂志》2017年06期 　论文类型：期刊论文

【摘要】：目的基于MRI常规序列信号、强化程度以及扩散特征,探讨最大增强比值和表观扩散系数(ADC)值对上皮型、纤维型及血管瘤型三种亚型脑膜瘤的鉴别诊断能力。方法回顾性分析经病理证实的33例上皮型、32例纤维型与11例血管瘤型脑膜瘤的术前MRI资料,量化三者的T_1WI、T_2WI信号强度及最大增强比值,测量瘤体实质、瘤周区及对侧正常脑实质ADC值。采用社会科学统计软件包SPSS 18.0版进行统计分析。采用卡方检验比较不同亚型脑膜瘤之间的T_1WI、T_2WI信号评分。应用两样本配对t检验比较同一亚型脑膜瘤的肿瘤实质与瘤周区、对侧正常脑实质之间的ADC值;应用独立样本t检验比较不同亚型脑膜瘤间的最大增强比值及ADC值。利用受试者工作特性曲线(ROC)来确定最大增强比值及ADC值对不同亚型脑膜瘤的诊断能力。结果纤维型、上皮型和血管瘤型脑膜瘤的最大强化程度依次增高(0.94±0.26,1.23±0.48,2.19±0.92),三者之间具有显著差异(P=0.006,P=0.007,P0.001);血管瘤型脑膜瘤瘤体实质平均ADC值[(11.60±1.04)×10~(-10)m~2/s],显著高于上皮型、纤维型[(8.75±1.78)×10~(-10)m~2/s、(8.55±2.11)×10~(-10)m~2/s](P0.01;P=0.001);利用ROC分析结果,以ADC值10.5×10~(-10)m~2/s、10.6×10~(-10_m~2/s为阈值鉴别血管瘤型与上皮型、血管瘤型与纤维型脑膜瘤的曲线下面积(AUC)较最大增强比值大,分别为0.927、0.94。结论与上皮型、纤维型相比,血管瘤型脑膜瘤具有明显不同的最大强化程度,且显著增高的ADC值有助于其鉴别诊断。
[Abstract]:Objective to investigate the effects of maximum enhancement ratio and apparent diffusion coefficient on epithelial type based on conventional sequence signals, enhancement degree and diffusion characteristics of MRI. Methods the MRI data of 33 cases of epithelial type meningioma and 11 cases of hemangioma type meningioma confirmed by pathology were analyzed retrospectively. The signal intensity and maximum enhancement ratio of T _ 1W _ I _ I _ I _ T _ 2WI were quantified to measure the substance of the tumor. The ADC values of peripheral and contralateral normal brain parenchyma were analyzed by SPSS 18.0. The T _ 1WI of meningiomas of different subtypes were compared by chi-square test. The tumor parenchyma of the same subtype of meningioma was compared with the surrounding area of the tumor and the ADC value of the contralateral normal cerebral parenchyma by using the T2WI signal score. T test of independent samples was used to compare the maximum enhancement ratio and ADC value among different subtypes of meningiomas. To determine the maximum enhancement ratio and ADC value in the diagnosis of different subtypes of meningioma. The maximum enhancement degree of epithelial and hemangioma meningiomas increased by 0.94 卤0.26 ~ 1.23 卤0.48 ~ 2.19 卤0.92). There was a significant difference among the three groups (P 0. 006, P 0. 007, P 0. 001). Mean ADC value of hemangioma meningioma. [(11.60 卤1.04) 脳 10 ~ (-10) -10 ~ (-1) / s), which was significantly higher than that of epithelial type and fibrous type. [8.75 卤1.78) 脳 10 ~ (10) -10 ~ (-1) m ~ (-1) / s (8.55 卤2.11) 脳 10 ~ (10) ~ 10 ~ (-1) / s ~ (2 /) ~ (2 / s) P ~ (0.01); P0. 001; Based on the results of ROC analysis, the threshold value of 10. 5 脳 10 ~ (-10) -10 ~ (-10) / s of ADC was used to distinguish hemangioma type from epithelial type as a threshold value of 10.6 脳 10 ~ (-10) ~ 10 ~ (-10) ~ 10 ~ (m-1) s. The area under curve of hemangioma type and fibrous meningioma was larger than that of maximum enhancement ratio, which was 0.927 ~ 0.94.Conclusion compared with epithelial type and fibrous type. Hemangioma meningiomas have significantly different degrees of maximum enhancement, and a significantly higher ADC value is helpful for differential diagnosis.
【作者单位】：大连医科大学附属第一医院放射科;
【分类号】：R445.2;R739.45
【正文快照】： 上皮型脑膜瘤、纤维型脑膜瘤及血管瘤型脑膜瘤是脑膜瘤分类中的三种亚型,WHO分级均为Ⅰ级[1],其中上皮型和纤维型脑膜瘤是最常见的亚型,而血管瘤型脑膜瘤的血管异常丰富,术中容易大量出血,术前准确诊断血管瘤型脑膜瘤,有助于临床制定更为合理的治疗方案及改善预后。MRI对脑膜

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