声触诊组织定量在胰腺局灶性病变鉴别诊断中的初步应用

发布时间：2018-01-18 09:04

本文关键词：声触诊组织定量在胰腺局灶性病变鉴别诊断中的初步应用　出处：《中国医学科学院学报》2017年02期 　论文类型：期刊论文

【摘要】：目的探讨声触诊组织定量(VTQ)鉴别胰腺局灶性病变应用价值。方法对51例胰腺占位患者行VTQ检查,分别获取病灶剪切波速(LSWV)、相邻胰腺实质剪切波速(PSWV)及剪切波速差值(DSWV)(DSWV=LSWVPSWV),对照病理结果或临床诊断,评估LSWV、PSWV和DSWV在胰腺局灶性病变的鉴别诊断价值。结果恶性组的LSWV和PSWV分别为(2.39±1.25)m/s(0.60~4.39 m/s)和(1.59±0.63)m/s(0.76~3.22 m/s);潜在恶性组的LSWV和PSWV分别为(1.92±1.07)m/s(0.79~4.00 m/s)和(1.43±0.41)m/s(0.80~2.23 m/s);良性组的LSWV和PSWV分别为(2.40±1.10)m/s(0.89~3.42 m/s)和(1.48±0.44)m/s(1.03~2.11 m/s);良、恶性组内LSWV和PSWV差异有统计学意义(P=0.029,P=0.005),潜在恶性组的LSWV和PSWV差异无统计学意义(P=0.087)。LSWV、PSWV和DSWV在3组间差异无统计学意义(P=0.401,P=0.638,P=0.625)。LSWV与病灶大小不相关(r=0.253,P0.05);LSWV与感兴趣区深度呈负相关(r=-0.413,P0.05)。结论利用VTQ鉴别诊断胰腺局灶性病变的价值有待进一步的研究。
[Abstract]:Objective to evaluate the clinical value of acoustic palpation tissue quantification (VTQ) in differentiating focal pancreatic lesions. Methods 51 patients with pancreatic mass were examined by VTQ and the focal shear wave velocities were obtained. Adjacent pancreatic parenchymal shear wave velocity (PSWV) and shear wave velocity difference (DSWV / DSWV / DSWV / LSWVPSWV) were used to evaluate LSWV. Value of PSWV and DSWV in differential diagnosis of focal pancreatic lesions results the LSWV and PSWV of malignant group were 2.39 卤1.25m / s (P < 0.05). 0.60 卤4.39 m / s) and 1.59 卤0.63 m / s / s 0.76 ~ 3.22 m / s / s; The LSWV and PSWV of the potentially malignant group were 1.92 卤1.07m / s 0.79 卤4.00 m / s and 1.43 卤0.41 m / s respectively (P < 0.05). 0.80 ~ 2.23 m / s ~ (-1); The LSWV and PSWV of benign group were 2.40 卤1.10 m / s 0.89 卤3.42 m / s and 1.48 卤0.44 m / s respectively (P < 0.05). 1.03 ~ 2.11 m / s ~ (-1); The difference between LSWV and PSWV in benign and malignant groups was statistically significant. There was no significant difference between LSWV and PSWV in potentially malignant group. There was no significant difference in DSWV and LSWV between the three groups. There was no correlation between the size of the lesion and the size of the lesion (P < 0. 638 or P 0. 05). There was a negative correlation between LSWV and the depth of the area of interest. Conclusion the value of VTQ in differential diagnosis of focal pancreatic lesions needs further study.
【作者单位】：中国医学科学院北京协和医学院北京协和医院超声医学科;
【基金】：公益性行业基金(201402001)~~
【分类号】：R576;R445.1
【正文快照】： 胰腺癌是最常见的胰腺原发性恶性肿瘤,其恶性度高,预后极差,5年总体生存率不超过5%。而且随着生活水平的提高、肥胖人群的增加及人口老龄化等原因,胰腺癌的发病率呈逐年上升趋势[1-2],对人类的健康造成了极大的危害。常规超声是胰腺病变首选的影像学筛查手段,能够有效地发现胰

【相似文献】