基于超声弹性成像的女性盆底肌肉定量评估方法

发布时间：2018-01-30 00:39

本文关键词： 盆腔器官脱垂肛提肌弹性成像肌肉评估　出处：《中国生物医学工程学报》2017年04期 　论文类型：期刊论文

【摘要】：女性盆底功能障碍性疾病是中老年女性的常见疾病,现已成为威胁女性健康的5种常见慢性疾病之一。盆底支撑结构中,盆底肌肉群的支撑作用至关重要,因此盆底肌肉评估对于女性盆底功能障碍性疾病的诊疗具有重要的临床价值。提出一种无创客观的肌肉运动分析方法,基于经会阴超声检测手段,同步获取50例具有不同脱垂程度女性主动收缩肌肉时的超声视频数据及阴道内压数据,应用二维弹性成像算法追踪盆底肌位移场,提取特征点的位移曲线,对比分析能有效完成指定动作的37例不同脱垂程度患者的位移结果,发现提取接近耻骨处特征点的切向位移参数(M_(Pu))与临床脱垂测量参数(L_(BP))具有相关性(r=-0.93),同时通过在指定的肌肉慢缩运动中的肌力维持时间均值和最大厚度均值对盆底肌的持续控制能力进行评估,结果与被试临床脱垂分级表现具有显著相关性。结果表明,这种方法可实现对盆底肌肉自身生物力学特性的客观定量评估,为临床脱垂诊断提供重要的参考价值。
[Abstract]:Pelvic floor dysfunction is one of the five common chronic diseases that threaten women's health. Pelvic floor muscles play an important role in the supporting structure of pelvic floor. Therefore, pelvic floor muscle assessment has important clinical value for the diagnosis and treatment of female pelvic floor dysfunction disease. A noninvasive and objective method of muscle motion analysis based on transperineal ultrasound was proposed. The ultrasonic video data and intravaginal pressure data of 50 women with different prolapse degrees were obtained simultaneously. The displacement field of pelvic floor muscle was tracked by two-dimensional elastic imaging algorithm and the displacement curve of characteristic points was extracted. The results of displacement in 37 patients with different prolapse degrees were compared and analyzed. It was found that there was a correlation between the extraction of tangential displacement parameters close to the characteristic point of pubis and the clinical prolapse measurement parameter (LSP). At the same time, the duration control ability of pelvic floor muscle was evaluated by the mean of muscle force maintenance time and maximum thickness in the specified muscle slow contraction. The results showed that this method could be used to evaluate the biomechanical characteristics of pelvic floor muscles. It provides important reference value for clinical prolapse diagnosis.
【作者单位】：深圳大学生物医学工程学院广东省生物医学信息检测与超声成像重点实验室;上海市东方医院吉安医院;深圳大学附属第一医院超声科;
【基金】：国家自然科学基金(61471243) 深圳市科技计划(SGLH20131010163759789,JCYJ20150731160834611,JCYJ20140414170821323)
【分类号】：R445.1;R711.5
【正文快照】： 引言女性盆底功能障碍性疾病(pelvic floordysfunction,PFD),是一种由于盆底支撑结构损伤而导致盆底脏器位置和功能异常的中老年女性常见疾病,主要表现为压力性尿失禁、盆腔器官脱垂和性功能障碍,现已成为威胁女性健康的5种常见慢性疾病之一[1]。1992年,Delancey教授提出了吊

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