亚急性期脑梗死的体素内不相干运动扩散加权成像

发布时间：2018-01-31 17:36

本文关键词： 脑梗死体素内不相干运动扩散磁共振成像脑血流　出处：《中国医学影像技术》2017年08期 　论文类型：期刊论文

【摘要】：目的探讨体素内不相干运动(IVIM)成像评价亚急性期脑梗死弥散和灌注情况的价值。方法回顾性分析35例亚急性期脑梗死患者的MR影像资料,包括常规DWI、IVIM成像及三维动脉自旋标记(3D-ASL)序列检查。通过常规DWI序列获得ADC图,IVIM序列获得纯水分子扩散系数(D)图、灌注相关扩散系数(D*)图、灌注分数(f)图,3D-ASL序列获得脑血流量(CBF)图。分别测量脑梗死灶及对照侧镜像区ADC值、D值、D*值、f值、CBF值及其相对值(rADC、rD、rD*、rf、rCBF)。比较脑梗死灶与对照侧镜像区各参数的差异,并分析rADC值与rD、rD*、rf值的相关性及rCBF值与rD、rD*、rf值的相关性。结果脑梗死灶ADC、D、D*、f、CBF值均较对照侧镜像区减低(P均0.05)。rADC值与rD、rf值呈正相关(r=0.687、0.601,P=0.005、0.018);rCBF值与rf值呈正相关(r=0.581,P=0.022)。结论 IVIM成像能同时提供亚急性期脑梗死的灌注及弥散信息,有助于进一步阐明亚急性期脑梗塞的机制。
[Abstract]:Objective to evaluate the diffusion and perfusion of subacute cerebral infarction by voxel incoherent motion imaging (IVIMI). Methods 35 cases of subacute cerebral infarction were retrospectively analyzed. Including routine DWI IVIM imaging and 3D arterial spin labeling 3D-ASL sequence examination. ADC map was obtained by routine DWI sequence. IVIM sequence obtained pure water molecular diffusion coefficient (D) map, perfusion correlation diffusion coefficient (D) map and perfusion fraction (f) map. The cerebral blood flow (CBF) map was obtained by 3D-ASL sequence. The ADC value and D value, D value, D value and relative value of ADC in the cerebral infarction area and the mirror image region of the control side were measured respectively. To compare the difference of the parameters between the cerebral infarction focus and the mirror image area of the control side, and to analyze the correlation between the rADC value and the rDdfr value, and the rCBF value and the rDd * value. Results the CBF values of cerebral infarction were significantly lower than those of the control group (P < 0.05). The rf value was positively correlated with 0.6870.601P0. 005 and 0. 018m. There was a positive correlation between rCBF value and RF value. Conclusion IVIM imaging can provide information of perfusion and diffusion of subacute cerebral infarction at the same time. It is helpful to further elucidate the mechanism of subacute cerebral infarction.
【作者单位】：暨南大学附属江门中医院医学影像科;
【基金】：江门市科技计划资助项目(201610029)
【分类号】：R445.2;R743.3
【正文快照】： 目前DWI及MR灌注成像已广泛应用于脑血管SPIRAL序列,TR　4　590ms,TE　10ms,层厚4mm,疾病诊断,尤其对急性期脑梗死的诊断[1]。体素内不层间距0,FOV　24cm×24cm,分辨力512(point)×8相干运动(intravoxel　incoherent　motion,IVIM)成像(arms),NEX　3,标记延迟时间(post-labeli

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