超声剪切波弹性成像在桥本甲状腺炎临床诊断中的价值

发布时间：2018-02-25 01:24

本文关键词： 桥本甲状腺炎剪切波弹性成像杨氏模量值甲状腺激素类　出处：《南方医科大学学报》2017年05期 　论文类型：期刊论文

【摘要】：目的探讨剪切波弹性成像技术(SWE)对桥本甲状腺炎(HT)不同分期的诊断价值。方法 104例经临床确诊的HT患者,根据甲状腺功能状态分为HT甲亢组(26例)、HT甲功正常组(29例)、HT亚临床甲减组(27例)和HT临床甲减组(22例)。同期选择健康志愿者作为健康对照组(50例)。利用SWE技术测量所有受检者甲状腺组织的杨氏模量值。采用Spearman相关分析法分析甲状腺组织杨氏模量值与甲状腺峡部厚度、甲状腺微粒体抗体(TMAb)、甲状腺球蛋白抗体(TGAb)滴度的相关性。结果健康对照组、HT甲亢组、HT甲功正常组、HT亚临床甲减组、HT临床甲减组甲状腺组织杨氏模量值呈递增趋势(P0.01)。HT甲亢组剪切波弹性模量值低于HT甲功正常组、HT亚临床甲减组、HT临床甲减组,差异均有统计学意义(P均0.05)。HT甲功正常组剪切波弹性模量值低于HT亚临床甲减组、HT临床甲减组,差异有统计学意义(P均0.05)。结论剪切波弹性成像杨氏模量值与桥本甲状腺炎不同分期患者临床表现有一定相关性,提示超声弹性成像对桥本甲状腺炎病程分期有一定的诊断价值。
[Abstract]:Objective to evaluate the diagnostic value of shear wave elastic imaging (SWE) in different stages of Hashimoto's thyroiditis. According to thyroid function status, 26 cases of hyperthyroidism group were divided into 29 cases of normal hyperthyroidism group and 27 cases of HT subclinical hypothyroidism group (n = 27) and 22 cases of HT clinical hypothyroidism group (n = 22). At the same time, healthy volunteers were selected as healthy control group (n = 50). The results were measured by SWE technique. The Young's modulus of thyroid tissue and the thickness of thyroid isthmus were analyzed by Spearman correlation analysis. Results the titer of thyroid microsomal antibody TMAbn and thyroglobulin antibody TGAb. results the thyroid tissue Young's modulus of normal hyperthyroidism group and normal HT subclinical hypothyroidism group showed an increasing trend of thyroid tissue Young's modulus in HT clinical hypothyroidism group. The value of shear wave elastic modulus in hyperthyroidism group was lower than that in HT subclinical hypothyroidism group, while that in HT subclinical hypothyroidism group was lower than that in HT subclinical hypothyroidism group. The values of shear wave elastic modulus in normal HT group were lower than those in HT subclinical hypothyroidism group and HT clinical hypothyroidism group. Conclusion the Young's modulus of shear wave elastic imaging is correlated with the clinical manifestations of different stages of Hashimoto's thyroiditis, suggesting that ultrasonic elastic imaging has certain diagnostic value in the course of Hashimoto's thyroiditis.
【作者单位】：解放军总医院第一附属医院超声科;
【基金】：国家自然科学基金(81141019) 海南省重点科技计划项目(ZDXM2014062) 海南省自然科学基金(813227) 海南省医学科研课题(琼2012PT-73)~~
【分类号】：R445.1;R581.4

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