声辐射力脉冲技术测量肝脏弹性值的影响因素分析

发布时间：2018-02-28 17:37

本文关键词： 超声弹性成像声辐射力脉冲剪切波速度肝脏　出处：《中国超声医学杂志》2017年07期 　论文类型：期刊论文

【摘要】：目的探讨声辐射力脉冲技术测量肝脏弹性值的影响因素。方法收集51例正常志愿者和177例慢性乙型肝炎患者的超声弹性检查结果,分析各因素对肝脏剪切波速度测量结果的准确度和稳定性的影响。结果两名医师测量一致性好(不同深度ICC均0.90)。正常人群中,深层组、男性组和皮下组织厚度薄组测量数据稳定性更好(CV:P=0.000、0.045、0.045);中老年组剪切波速度(SWV)高于青年组(P=0.004);不同体质量指数(BMI)分组间CV有差异(P=0.046)。肝脏SWV和慢乙肝患者肝纤维化程度呈高度正相关性(Sprearmanρ=0.753,P=0.000)。轻度肝纤维化患者,男性SWV高于女性,CV低(P=0.047、0.045);中老年组SWV高于青年组(P=0.003)。中度肝纤维化患者,中老年组SWV高于青年组(P=0.009),重度纤维化患者各因素组间无统计学差异。结论应用声辐射力脉冲技术测量肝脏弹性数值,在不同人群中需考虑不同因素的影响,客观分析测量结果的意义。
[Abstract]:Objective to investigate the factors influencing the measurement of liver elasticity by acoustic radiation pulse technique. Methods the results of ultrasonic elasticity in 51 normal volunteers and 177 patients with chronic hepatitis B were collected. The effect of various factors on the accuracy and stability of hepatic shear wave velocity measurement was analyzed. Results the two physicians had a good consistency (ICC of different depths were 0.90). The stability of the measured data was better in the male group and the thin subcutaneous tissue thickness group. The shear wave velocity in the middle and old age group was higher than that in the young group. The CV was different among the groups with different body mass index (BMI). The liver SWV and chronic hepatitis B patients had liver fibrosis degree. Sprearman 蟻 0.753P 0.0000.000. Patients with mild hepatic fibrosis, The SWV of male was higher than that of female, the SWV of middle and aged group was higher than that of young group. The SWV in the middle and old age group was higher than that in the young group, and there was no statistical difference among the factors in the patients with severe fibrosis. Conclusion the effect of different factors should be taken into account in the measurement of liver elasticity by acoustic radiation pulse technique. Objective analysis of the significance of the measurement results.
【作者单位】：北京大学第一医院超声诊断中心;
【分类号】：R445.1;R512.62

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