实时剪切波弹性成像在不同大小TI-RADS 3～4类甲状腺结节鉴别诊断中的应用

发布时间：2018-03-02 09:47

  本文关键词： 剪切波弹性成像 甲状腺结节 TI-RADS ~类　出处：《南京医科大学学报(自然科学版)》2017年02期 　论文类型：期刊论文

【摘要】：目的:探讨实时剪切波弹性成像(shear wave elastography,SWE)在不同大小甲状腺TI-RADS 3~4类结节鉴别诊断中的应用。方法:常规超声观察164例患者(共197个结节)甲状腺结节的边界、内部回声、是否合并钙化、纵横比、内部及周边血流情况等,依据甲状腺TI-RADS分类方法对相应的甲状腺状腺结节进行分类,同时进行剪切波弹性成像,记录结节杨氏模量最大值(Emax),绘制ROC曲线,获得鉴别诊断甲状腺良恶性结节的Emax最佳界值。其中TI-RADS 3~4类结节186个,分直径≤10 mm组(Ⅰ组)和直径10 mm组(Ⅱ组)。以病理结果为金标准,分别绘制ROC曲线,评价Emax值在Ⅰ、Ⅱ组病变中的应用价值。结果:杨氏模量Emax界值为52.5 k Pa。Ⅰ组和Ⅱ组的敏感性、准确性及特异性分别为57.4%、66.2%及90.0%和87.5%、79.5%及68.8%,ROC曲线下面积(area under the curve,AUC)分别为0.810和0.842。结论:SWE界值鉴别诊断甲状腺良恶性结节差异有统计学意义;SWE对10 mm甲状腺结节良恶性鉴别诊断更有应用价值;SWE对≤10 mm甲状腺结节应用价值有限。
[Abstract]:Objective: to investigate the application of real-time shear wave elastography wave (ESR) in differential diagnosis of thyroid TI-RADS 3O 4 nodules of different sizes. Methods: the boundary and internal echo of thyroid nodules in 164 patients (197 nodule) were observed by conventional ultrasound. With or without calcification, aspect ratio, internal and peripheral blood flow, the thyroid gland nodules were classified according to the thyroid TI-RADS classification method, and the shear wave elastic imaging was performed at the same time. The maximum value of Young's modulus was recorded and the ROC curve was drawn to obtain the best value of Emax for differential diagnosis of benign and malignant thyroid nodules. The diameter 鈮，

本文编号：1556005