基于生存分析的美沙酮维持治疗患者脱失及影响因素研究

发布时间：2018-03-10 15:05

  本文选题：美沙酮维持治疗　切入点：脱失　出处：《河南预防医学杂志》2017年04期 　论文类型：期刊论文

【摘要】：目的探讨美沙酮维持治疗患者脱失及其影响因素,为提供干预措施提供科学依据。方法收集福田区和南山区2009-2014年所有美沙酮维持治疗患者相关信息,使用Kaplan-Meier法进行单因素分析,根据单因素结果选择有意义的变量进入Cox比例风险模型进行生存分析。结果共收集694例研究对象,5年累计脱失率为82.42%,研究发现无业,独居,靠临时工资生活,公安部门介绍参加治疗,静脉和其他方式混合吸毒,吸毒年限在10~15 a,日服用剂量≤30mL,合并感染丙肝,梅毒或艾滋病均为美沙酮维持治疗门诊患者脱失的危险因素。结论美沙酮门诊脱失率较高,严重影响门诊治疗效果,应根据危险因素,提供针对性的干预措施,有效降低门诊脱失率。
[Abstract]:Objective to investigate the loss of methadone maintenance therapy and its influencing factors, and to provide scientific basis for intervention measures. Methods the information of all methadone maintenance patients from 2009 to 2014 in Futian District and Nanshan District was collected and single factor analysis was performed by Kaplan-Meier method. According to the single factor results, significant variables were selected into the Cox proportional risk model for survival analysis. Results A total of 694 subjects were collected. The cumulative loss rate for 5 years was 82.42. The study found that they were unemployed, living alone and living on temporary wages. The public security department introduced taking part in treatment, intravenous and other mixed drug use. The drug use period was 1015a, daily dose 鈮，

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