ICU重症内科患者感染鲍氏不动杆菌的相关危险因素研究

发布时间：2018-03-16 20:17

本文选题：鲍氏不动杆菌　切入点：感染　出处：《中华医院感染学杂志》2017年11期 　论文类型：期刊论文

【摘要】：目的研究分析ICU重症内科患者感染鲍氏不动杆菌的相关危险因素。方法选取2013年10月-2015年10月医院ICU重症内科病房患者469例为研究对象,统计鲍氏不动杆菌感染率,对发生鲍氏不动杆菌感染患者相关因素进行单因素分析,并将单因素中显著差异变量纳入多因素logistic回归分析,同时记录28d患者死亡率。结果 ICU重症内科病房469例患者中,78例感染鲍氏不动杆菌,感染率为16.6%;GCS评分、血清白蛋白、MBP、合并真菌感染、病程中出现休克、机械通气7d与患者发生鲍氏不动杆菌感染有关;多因素分析显示,血清白蛋白25g/L、合并真菌感染、病程中出现休克是患者发生鲍氏不动杆菌感染的独立危险因素;28d后78例感染鲍氏不动杆菌患者死亡33例,死亡率是42.3%。结论 ICU重症患者鲍氏不动杆菌感染率和死亡率高,血清白蛋白25g/L、合并真菌感染、病程中出现休克是患者发生鲍氏不动杆菌感染的独立危险因素。
[Abstract]:Objective to study and analyze the risk factors of Acinetobacter baumannii infection in patients with ICU. Methods from October 2013 to October 2015, 469 ICU patients were selected as the study subjects, and the infection rate of Acinetobacter baumannii was counted. Univariate analysis was performed on the related factors of patients with Acinetobacter baumannii infection, and significant differences in single factors were included in multivariate logistic regression analysis. Results 78 patients were infected with Acinetobacter baumannii, the infection rate was 16.6G CS score, serum albumin MBP, fungal infection, shock occurred in the course of the disease. Mechanical ventilation for 7 days was associated with Acinetobacter baumannii infection, multivariate analysis showed that serum albumin 25 g / L, complicated with fungal infection, Shock was an independent risk factor for Acinetobacter baumannii infection in patients with ICU. After 28 days, 33 patients died of Acinetobacter baumannii and the mortality rate was 42.3. Conclusion the infection rate and mortality rate of Acinetobacter baumannii in ICU patients is high. Serum albumin 25 g / L, accompanied by fungal infection and shock in the course of the disease, was an independent risk factor for Acinetobacter baumannii infection.
【作者单位】：绍兴文理学院附属医院ICU;浙江中医药大学第一临床医学院;
【基金】：浙江省医药卫生一般研究计划基金资助项目(2015KYA167)
【分类号】：R459.7

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