DCE-MRI定量参数结合DWI对前列腺癌的诊断价值

发布时间：2018-03-16 20:26

本文选题：前列腺癌　切入点：DCE-MRI　出处：《中国医学计算机成像杂志》2017年03期 　论文类型：期刊论文

【摘要】：目的:探讨1.5T磁共振动态增强(DCE-MRI)定量参数及弥散加权成像(DWI)对前列腺癌的诊断价值。方法:收集我院74例经手术或穿刺活检病理证实的前列腺疾病患者,其中前列腺癌(PCa)32例,前列腺增生(BPH)42例。均行磁共振平扫、DCE-MRI和DWI扫描,参照MR图像及病理,选择感兴趣区(ROI)并测定DCE-MRI定量参数K~(trans)、K_(ep)、V_e及弥散加权表观弥散系数(ADC)值,分析两组间K~(trans),K_(ep),V_e值、DWI图像信号特点、ADC值,做统计学分析。结果:两组间K~(trans)、K_(ep)值差异有统计学意义(P0.05),V_e差异无统计学意义(P=0.63);两组间DWI信号差异及ADC值差异均有统计学意义(P0.05)。DCE-MRI结合DWI-ADC值对Pca诊断的敏感度、特异度和准确度高于单纯的DCE-MRI或DWI检查。结论:DCE-MRI定量分析结合DWI成像及ADC值可有效提高对Pca的诊断效能。
[Abstract]:Objective: to investigate the diagnostic value of DCE-MRI quantitative parameters and diffusion weighted imaging (DWI) at 1.5T MRI in the diagnosis of prostate cancer. Methods: 74 patients with prostatic diseases confirmed by operation or biopsy were collected in our hospital. 42 cases of benign prostatic hyperplasia (BPH) were examined by Mr plain scan DCE-MRI and DWI. According to Mr and pathology, the region of interest (ROI) was selected. The quantitative parameters of DCE-MRI were measured and the DCE-MRI quantitative parameters were measured, and the diffusion weighted apparent diffusion coefficient (ADCC) was measured, and the signal characteristics of DWI were analyzed between the two groups. Results: there was no significant difference in DWI signal and ADC between the two groups in the diagnosis of Pca, there was significant difference between the two groups in the value of Ke. DCE-MRI combined with DWI-ADC, there was no significant difference between the two groups in the diagnosis of Pca, and there was no significant difference between the two groups in the DWI signal and the difference of the ADC value in the diagnosis of Pca, and there were significant differences between the two groups in the sensitivity of the two groups in the diagnosis of Pca, and there was no significant difference between the two groups in the diagnosis of Pca. The specificity and accuracy were higher than those of DCE-MRI or DWI alone. Conclusion the diagnostic efficiency of Pca can be improved effectively by combining the quantitative analysis of DWI with DWI and ADC.
【作者单位】：上海交通大学医学院附属新华医院崇明分院放射科;
【基金】：卫计委科研基金项目No.201540148 上海交通大学医学院科技基金项目No.14XJ22013 上海市崇明县科委启明星项目No.CQYL2014-09~~
【分类号】：R445.2;R737.25

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