西藏地区腹膜透析患者现状调查

发布时间：2018-03-18 05:29

本文选题：腹膜透析　切入点：慢性肾脏病　出处：《肾脏病与透析肾移植杂志》2017年05期 　论文类型：期刊论文

【摘要】：目的:分析西藏地区腹膜透析患者现状,为提高腹膜透析质量提供依据。方法:回顾性分析2011年5月至2016年6月在西藏自治区人民医院接受腹膜透析治疗的患者的临床及实验室资料,用单因素COX回归分析腹膜炎及死亡事件的相关因素。结果:56例腹膜透析患者,导致终末期肾病的首要病因是肾小球肾炎(43例,76.8%)、其次为糖尿病肾病(4例,7.1%)。腹膜炎的发病率为1/35.8患者月,是导致技术失败的首要原因。第1、2、3年的患者生存率分别为95.8%、83.5%、79.9%,主要死亡原因是肺部感染和心功能不全。C反应蛋白与死亡风险增加显著相关(HR 1.03,95%CI 1.01~1.05,P=0.004)。结论:西藏地区腹膜透析患者进入终末期肾病的首要病因是肾小球肾炎。本组患者腹膜炎发生率偏高,导致死亡的主要原因是肺部感染和心功能不全。C反应蛋白升高是死亡的危险因素。
[Abstract]:Objective: to analyze the present situation of peritoneal dialysis patients in Tibet. Methods: the clinical and laboratory data of patients treated with peritoneal dialysis in the people's Hospital of Tibet Autonomous region from May 2011 to June 2016 were analyzed retrospectively. Univariate COX regression analysis was used to analyze the related factors of peritonitis and death events. The primary cause of end-stage nephropathy was glomerulonephritis in 43 cases, followed by diabetic nephropathy in 4 cases. The incidence of peritonitis was 1 / 35.8 months. The survival rate of the patients at the 1st and 3rd year was 95.8% 83.5% and 79.9% respectively. The main causes of death were pulmonary infection and cardiac insufficiency. C reactive protein was significantly associated with the increased risk of death. Conclusion: the abdominal cavity in Tibet is associated with a significant increase in the risk of death. Glomerulonephritis is the primary cause of end-stage nephropathy in patients with membrane dialysis. The incidence of peritonitis in this group is relatively high. The main causes of death were pulmonary infection and increased. C reactive protein were risk factors of death.
【作者单位】：西藏自治区人民医院肾脏内科;北京大学第一医院肾内科北京大学肾脏病研究所;
【基金】：西藏自治区自然科学基金项目(20152R-14-50)
【分类号】：R459.5

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