超声及磁共振成像对血友病膝关节健康状况的相关性评估

发布时间：2018-03-28 07:13

本文选题：血友病　切入点：膝关节　出处：《重庆医科大学》2017年硕士论文

【摘要】：目的以磁共振成像为参照,探讨高频超声对血友病性关节病的特征。方法收集44名血友病患者中70例膝关节行超声检查,其中11名小于18岁的血友病患者中16例膝关节完成磁共振成像(MRI)检查,同时对膝关节按照2.1版血友病关节健康评估表(Hemophilia Joint Health Score,HJHS)评价其健康状况,分析超声评分与年龄及出血次数的相关性,并以磁共振成像为参照,分析关节超声特点及其与、MRI及健康状况之间的相关性。结果血友病性关节病变严重程度与血友病的严重程度无明显相关性(F=0.013,P=0.987),随着年龄增加、出血次数增多,关节病变越重;对于关节病变早期的滑膜增厚及软骨改变的检出,超声及MRI检查无明显差异(P0.05);超声检查与MRI存在明显相关相关性(r=0.702,P0.05),超声检查与HJHS2.1之间存在明显相关性(r=0.659,P0.05)MRI评分与HJHS2.1之间存在明显的相关性(r=0.640,P0.05)。结论随着年龄及平均出血次数的增加均能使关节病变越重,高频超声对于血友病性关节病的早期诊断有重要意义,且因其经济、有效、方便、安全等特征,对临床具有较好的实用性。
[Abstract]:Objective to study the characteristics of hemophilia arthropathy by high frequency ultrasound (HFUS) compared with magnetic resonance imaging (MRI) methods 70 of 44 hemophilia patients were examined by ultrasonography. Sixteen of 11 hemophilia patients under the age of 18 completed MRI MRI, and their health status was evaluated according to Hemophilia Joint Health ScoreHJHS2. The correlation of ultrasound score with age and bleeding frequency was analyzed, and magnetic resonance imaging (MRI) was used as a reference. Results there was no significant correlation between the severity of hemophilia and the severity of hemophilia. For early synovial thickening and cartilage change detection, There was no significant difference between ultrasound and MRI examination (P 0.05); there was a significant correlation between ultrasound examination and MRI. There was a significant correlation between ultrasound examination and HJHS2.1. There was a significant correlation between ultrasound examination and HJHS2.1. There was a significant correlation between MRI score and HJHS2.1. Conclusion with age and average bleeding, there is a significant correlation between MRI score and HJHS2.1. An increase in the number of times can make the joint disease worse. High frequency ultrasound is of great significance for the early diagnosis of hemophilia arthrosis, and has good practicability for clinical practice because of its economic, effective, convenient and safe characteristics.
【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R445;R554.1

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