~1H-MRS在慢性血吸虫肝病诊断中的价值

发布时间：2018-04-04 04:47

  本文选题：血吸虫性　切入点：肝疾病　出处：《临床放射学杂志》2017年11期

【摘要】：目的探讨~1H-MRS在慢性血吸虫肝病中的诊断价值。方法分别对经临床及病理证实的慢性血吸虫肝病患者30例(肝病组)和健康志愿者38名(对照组)行肝脏常规MRI和~1H-MRS检查,测量相关代谢物[水(H_2O)、胆碱(Cho)、脂质(Lip)]的峰值及峰下面积,并进行统计分析。结果慢性血吸虫肝病组和对照组MRS图像主要显示为H_2O峰(4.6 ppm)、Cho峰(3.2 ppm)和Lip峰(1.3 ppm);慢性血吸虫肝病组~1H-MRS H_2O峰、Lip峰峰值及峰下面积均低于对照组,且有统计学意义(P0.05);Cho峰峰值及峰下面积与对照组差异无统计学意义(P0.05)。受试者工作特征曲线(ROC)曲线下面积(AUC)从大到小依次为H_2O峰值、H_2O下面积、Lip峰下面积、Lip峰值,其AUC分别为0.805、0.761、0.729、0.668,特异度分别为0.600、0.733、0.670、0.633,敏感度分别为0.921、0.737、0.789、0.737;联合得到MRS的AUC是0.861、特异度0.684、敏感度0.867。结论 ~1H-MRS对慢性血吸虫肝病诊断有一定价值,其中H_2O峰值及峰下面积诊断效能最高。
[Abstract]:Objective to investigate the diagnostic value of 1 H-Mrs in chronic schistosomiasis liver disease.Methods liver routine MRI and 1H-MRS were performed in 30 patients with chronic schistosomiasis liver disease (liver disease group) and 38 healthy volunteers (control group).The peak value and subpeak area of related metabolites [H2OO, Cho, Lipin] were measured and analyzed statistically.Results the MRS images of chronic schistosomiasis liver disease group and control group mainly showed that the peak of H2O was 4.6 ppm-1. 2 ppm) and the peak of Lip was 1. 3 ppmm.The peak value and subpeak area of 1 H-MRS H2O peak in chronic schistosomiasis liver disease group were lower than those in control group.There was no significant difference between the control group and the control group in the peak value of Cho and the area under the peak.鍙楄瘯鑰呭伐浣滅壒寰佹洸绾，

本文编号：1708432