低剂量CT结合迭代靶重建技术在健康体检筛查早期肺癌中的应用价值

发布时间：2018-04-04 05:09

本文选题：低剂量CT　切入点：迭代靶重建技术　出处：《浙江医学》2017年06期

【摘要】：目的探讨低剂量CT结合迭代靶重建(IR)技术在健康体检筛查早期肺癌中的应用价值。方法选取行肺部低剂量CT检查的健康体检者100例(有结节病变者优先选取),与同期行常规剂量CT检查的普通患者100例进行比较。由2位经验丰富的放射科医师独立进行图像解读与评价,并对结节性质进行定性诊断,再与病理切片进行对照;测量并比较两组图像噪声、CT值、信噪比(SNR)、辐射剂量参数[剂量长度乘积(DLP)、容积剂量指数(CTDIvol)、有效剂量(ED)]。结果低剂量组DLP、CTDIvol、ED均明显低于常规剂量组(均P0.05)。2位医师对低剂量组、正常剂量组的主观图像质量评价结果一致,均符合诊断要求;两组纵隔窗、肺窗主观图像质量评价结果比较,差异均无统计学意义(均P0.05)。低剂量组图像噪声、SNR均高于常规剂量组(均P0.05);两组CT值比较差异无统计学意义(P0.05)。低剂量组中有肺结节病变者57例,其中确诊为早期肺癌7例,炎性病灶20例,钙化及瘢痕结节30例;CT诊断结果与病理诊断结果相符。结论低剂量CT结合IR技术可在健康体检筛查早期肺癌中推广应用。
[Abstract]:Objective to evaluate the value of low dose CT combined with iterative target reconstruction (IRR) in early lung cancer screening.Methods A total of 100 patients with pulmonary low dose CT examination were selected, and 100 patients with nodular lesions were compared with those who received conventional CT examination at the same time.The images were interpreted and evaluated independently by two experienced radiologists, the nature of the nodules was diagnosed qualitatively, and then compared with the pathological sections, the noise CT values of the two groups of images were measured and compared.Signal-to-noise ratio (SNR), radiation dose parameters [dose length product (DLPN), volumetric dose index (CTD), effective dose (EDV)].Results the results of subjective image quality evaluation in low dose group and normal dose group were consistent, and the results of subjective image quality evaluation of mediastinal window and pulmonary window were compared between the two groups.The difference was not statistically significant (P 0.05).The image noise SNR of the low dose group was higher than that of the conventional dose group (all P 0.05), and the difference of CT value between the two groups was not statistically significant (P 0.05).In the low dose group, 57 cases had pulmonary nodule lesions, including 7 cases of early lung cancer, 20 cases of inflammatory lesions, 30 cases of calcification and scar nodules.Conclusion low dose CT combined with IR technique can be widely used in early lung cancer screening.
【作者单位】：宁波市第一医院影像科;宁波大学医学院;
【分类号】：R734.2;R730.44

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