fMRI参数与直肠癌患者病理学分期及淋巴结转移的关系

发布时间：2018-04-07 18:35

本文选题：直肠癌　切入点：功能性磁共振成像　出处：《山东医药》2017年09期

【摘要】：目的探讨功能性磁共振成像(f MRI)方法扩散加权成像(DWI)和动态对比增强磁共振成像(DCEMRI)参数与直肠癌患者病理学T分期、Dukes分期及淋巴结转移的相关性。方法通过对78例经病理检查证实的直肠癌患者DWI及DCE-MRI图像进行回顾性分析,获得DWI参数ADC值及DCE-MRI定量参数Ktrans、Ve、Kep值,进一步对这些参数值与肿瘤的T分期、Dukes分期及有无淋巴结转移进行相关性分析。结果直肠癌患者的DWI参数ADC值随肿瘤T分期、Dukes分期的增加及淋巴结转移而减低(P均0.05)。DCE-MRI定量参数Ktrans、Ve值随肿瘤T分期、Dukes分期的增加及淋巴结转移而升高(P均0.05);不同T分期、Dukes分期、有无淋巴结转移者Kep值差异无统计学意义(P均0.05)。结论 f MRI中DWI参数ADC值及DCE-MRI定量参数Ktrans、Ve值与直肠癌患者的病理学分期及淋巴结转移有一定关系,能为直肠癌术前分期提供有价值的信息。
[Abstract]:Objective to investigate the correlation between DWI (diffusion weighted imaging) and DCEMRI (dynamic contrast enhanced magnetic resonance imaging) parameters and pathological T staging Dukes staging and lymph node metastasis in rectal cancer patients with functional magnetic resonance imaging (fMRI).Methods the DWI and DCE-MRI images of 78 patients with rectal cancer confirmed by pathological examination were retrospectively analyzed, and the ADC values of DWI parameters and the Ktransvee Kep values of DCE-MRI quantitative parameters were obtained.Furthermore, the correlation between these parameters and T stage Dukes staging and lymph node metastasis was analyzed.There was no significant difference in Kep between patients with and without lymph node metastasis (P < 0.05).Conclusion the ADC value of DWI parameter in f MRI and the value of DCE-MRI quantitative parameter KtransVe are related to the pathological stage and lymph node metastasis of rectal cancer patients, which can provide valuable information for preoperative staging of rectal cancer.
【作者单位】：华北理工大学附属医院;
【基金】：河北省科技计划资助项目(162777139)
【分类号】：R445.2;R735.37

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