能谱CT定量参数鉴别诊断原发性胃淋巴瘤和胃癌

发布时间：2018-04-09 14:11

本文选题：淋巴瘤　切入点：胃肿瘤　出处：《中国医学影像技术》2017年02期

【摘要】：目的探讨能谱CT(GSI)定量参数鉴别诊断原发性胃淋巴瘤(PGL)和胃癌(GC)的价值。方法收集PGL患者16例(PGL组)、GC患者24例(GC组),行平扫和GSI双期增强扫描。测量两组肿瘤病灶的单能量CT值、碘(水)基物质浓度和有效原子序数(Z_(eff)),计算标化碘浓度(NIC)、能谱曲线斜率(λ_(HU))、标化原子序数(Z_(eff-c))。采用独立样本t检验对各定量参数进行比较分析,运用ROC曲线评估其诊断效能。结果 PGL组增强双期40~90keV图像λ_(HU)均低于GC组(t=2.90、3.69,P=0.008、0.001)。PGL组动脉期40keV、静脉期40~120keV单能量CT值均低于GC组(P均0.05);PGL组70keV增强双期NIC、动脉期标化水浓度均低于GC组,PGL组静脉期Z_(eff-c)高于GC组(P均0.05);静脉期70keV单能量图像以λHU=2.63mg/cm3为阈值鉴别诊断PGL和PC的敏感度和特异度分别为62.5%和100%。结论GSI定量参数对PGL和GC的鉴别诊断有一定实用价值。
[Abstract]:Objective to evaluate the differential diagnosis of primary gastric lymphoma (PGL) and gastric carcinoma (GC) by energy dispersive CTI GSI.Methods Sixteen patients with PGL and 24 patients with GC were examined with plain scan and dual phase GSI enhanced scan.The single energy CT value, the concentration of iodine (water)-based substance and the effective atomic number of the two groups were measured. The standard iodine concentration was calculated. The slope of the energy spectrum curve was calculated.The independent t-test was used to compare and analyze the quantitative parameters and the ROC curve was used to evaluate the diagnostic effectiveness.The sensitivity and specificity of single energy image of 70keV in venous phase for differential diagnosis of PGL and PC by 位 HU=2.63mg/cm3 threshold were 62.5% and 100%, respectively.Conclusion quantitative parameters of GSI are useful for differential diagnosis of PGL and GC.
【作者单位】：广西医科大学附属肿瘤医院影像诊断中心;广西医科大学研究生学院;广西医科大学附属肿瘤医院淋巴血液肿瘤科;
【基金】：广西医疗卫生适宜技术研究与开发课题(S201417-06) 广西研究生教育创新计划(YCBZ2014029)
【分类号】：R735.2;R730.44

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