高分辨率DWI-RESOLVE序列对直肠癌术前分期的应用价值

发布时间：2018-04-11 06:10

本文选题：直肠癌 + 磁共振弥散加权成像　；参考：《中国医学计算机成像杂志》2017年03期

【摘要】：目的:本研究旨在探讨高分辨率DWI-RESOLVE序列对直肠癌术前T分期的价值。方法:回顾性分析在我院经术后病理证实的直肠腺癌患者40例(T1-T2为A组,T3-T4为B组)。全部研究对象均完成RESOLVE序列扫描,b值=0、1000s/mm~2。两名医师独立分析图像,得到感兴趣区的ADC值。计算组内相关系数(ICC)分析两名医师测量结果的一致性。根据病理结果制作受试者操作特性曲线(ROC),计算曲线下面积(AUC),分析得出最佳诊断阈值及敏感度和特异度。结果:40例直肠癌术后病理T分期:T1-T2 17例,T3-T4 23例。A组的平均ADC值为(1.230±0.160)×10~(-3)mm~2/s(医师1)和(1.200±0.166)×10~(-3)mm~2/s(医师2),高于B组的平均ADC值(0.973±0.216)×10~(-3)mm~2/s(医师1)和(0.948±0.181)×10~(-3)mm~2/s(医师2)。两名医师测量参数的ICC系数是0.947。ROC曲线下面积是0.850,敏感度76.47%,特异度78.26%,诊断阈值为1.13×10~(-3)mm~2/s。结论:RESOLVE序列对于术前判断直肠癌病灶是否突破固有肌层具有较高的参考价值。
[Abstract]:Objective: to investigate the value of high-resolution DWI-RESOLVE sequence in preoperative T-staging of rectal cancer.Methods: 40 cases of rectal adenocarcinoma confirmed by pathology in our hospital were retrospectively analyzed.All the subjects completed the RESOLVE sequence scan and the b value was 0 / 1000 s / m ~ (-1) / m ~ (2).The two physicians analyzed the images independently and obtained the ADC value of the region of interest.The correlation coefficient (ICC) was calculated to analyze the consistency of the two physicians' measurements.According to the pathological results, the operating characteristic curve was made, and the area under the curve was calculated. The best diagnostic threshold, sensitivity and specificity were obtained.The ICC coefficient of the two physicians was 0.850 under the 0.947.ROC curve, the sensitivity was 76.47, the specificity was 78.26, and the diagnostic threshold was 1.13 脳 10 ~ (-3) mm ~ (-1) / s.ConclusionThe solution sequence has a high reference value for preoperative diagnosis of rectal cancer whether or not the lesion breaks through the lamina propria muscularis.
【作者单位】：第二军医大学附属长海医院放射科;
【分类号】：R445.2;R735.37

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