225例早产儿血培养致病菌分布及耐药性分析

发布时间：2018-04-20 21:21

本文选题：早产儿 + 血培养　；参考：《中华医院感染学杂志》2017年21期

【摘要】：目的了解医院早产儿血培养的菌株分布及耐药性,为指导临床合理应用抗菌药物提供客观依据。方法对2010年1月-2015年12月225例早产儿血培养结果采用WHONET5.6进行菌株和药物敏感性分析,数据用Excel进行统计处理。结果共采集标本225份,检出病原菌225株,其中革兰阴性菌108株占48.0%,革兰阳性菌99株占44.0%,真菌18株占8.0%;药敏结果显示革兰阴性菌对碳青霉烯类抗菌药物均敏感;革兰阳性菌中凝固酶阴性葡萄球菌属对青霉素、氨苄西林耐药率为97.5%,金黄色葡萄球菌对青霉素、氨苄西林耐药率为100.0%,对万古霉素、利奈唑胺敏感率为100.0%。结论合理选择抗菌药物,可减少耐药菌株的产生,提高治愈率并控制交叉感染。
[Abstract]:Objective to investigate the distribution and drug resistance of blood culture strains of premature infants in hospital, and to provide objective basis for rational clinical application of antibiotics. Methods from January 2010 to December 2015, the blood culture results of 225 premature infants were analyzed by WHONET5.6 and drug sensitivity, and the data were analyzed by Excel. Results 225 samples were collected and 225 strains of pathogenic bacteria were detected, of which 108 strains were Gram-negative bacteria (48.0%), 99 Gram-positive bacteria (44.0 strains) and 18 fungi strains (8.0%). In Gram-positive bacteria, coagulase negative staphylococcus belongs to penicillin, ampicillin resistant rate is 97.50.Staphylococcus aureus is resistant to penicillin, ampicillin resistance rate is 100.00.The sensitivity to vancomycin and linazolamine is 100.0. Conclusion rational selection of antimicrobial agents can reduce the production of drug-resistant strains, improve the cure rate and control cross infection.
【作者单位】：温州医科大学附属第二医院育英儿童医院医学检验中心;
【分类号】：R446.5;R722.6

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