血管内导管相关性血流感染的临床分布特征及耐药分析

发布时间：2018-04-21 19:07

本文选题：血管内导管相关性血流感染 + 病原菌　；参考：《中国抗生素杂志》2017年07期

【摘要】：目的分析血管内导管相关性血流感染的临床分布特征及耐药性,指导血管内导管相关性血流感染的治疗。方法对医院确诊为血管内导管相关性血流感染的45例患者进行回顾性分析临床分布特征及其耐药性。结果 45例患者共检出47株病原菌,其中革兰阳性菌占38.29%,以葡萄球菌属为主,占25.53%,革兰阴性菌占34.04%,以不动杆菌属和肠杆菌科菌属为主,分别占12.76%和14.89%,真菌占27.66%;革兰阳性菌对替考拉宁和万古霉素耐药率均为0,对利福平和四环素耐药率为29.41%和47.06%;革兰阴性菌对阿米卡星和亚胺培南的耐药率为43.75%和37.50%;发现1株对氟康唑、伊曲康唑和伏立康唑耐药的热带念珠菌。结论了解血管内导管相关性血流感染临床分布特征及耐药性,有助于指导血管内导管相关性血流感染的治疗。
[Abstract]:Objective to analyze the clinical distribution characteristics and drug resistance of intravascular catheter related blood flow infection and to guide the treatment of intravascular catheter related blood flow infection. Methods the clinical distribution characteristics and drug resistance of 45 patients with intravascular catheter related blood flow infection were retrospectively analyzed. Results 47 diseases were detected in 45 patients. Among them, Gram-positive bacteria accounted for 38.29%, which accounted for 25.53% of Staphylococcus, 34.04% Gram-negative bacteria, 12.76% and 14.89% of Acinetobacter and 14.89% of Enterobacteriaceae, 27.66% of fungi, 0 with Gram-positive bacteria to teicoplanin and vancomycin, and 29.41% and 47.06% to rifampicin and tetracycline. The resistance rate of Gram-negative bacteria to Amikacin and imipenem was 43.75% and 37.50%. 1 strains of Candida tropicalis were found to be resistant to fluconazole, itraconazole and voriconazole. Conclusion the clinical distribution characteristics and drug resistance of intravascular catheter related blood flow infection are helpful to guide the treatment of catheter related blood flow infection in the blood tube.

【作者单位】：宁夏医科大学总医院;宁夏银川市第一人民医院;宁夏医科大学;
【基金】：国家自然科学基金(No.81560701)
【分类号】：R446.5

【相似文献】