2015年河北省53所医院临床分离肺炎链球菌耐药性监测

发布时间：2018-04-24 22:00

本文选题：肺炎链球菌 + 耐药性　；参考：《中国感染与化疗杂志》2017年06期

【摘要】：目的调查2015年河北省53所医疗机构临床分离的肺炎链球菌对常用抗菌药物的耐药现状,为区域内临床合理用药提供支持。方法按细菌耐药性监测方案要求,收集河北省53所细菌耐药性监测网成员单位临床分离的肺炎链球菌数据,药敏试验参照CLSI 2014标准,用WHONET 5.6分析数据。结果共分离肺炎链球菌2 408株,占革兰阳性菌分离数第3位。分离的肺类链球菌对万古霉素、莫西沙星的敏感率均95%;而对红霉素、克林霉素、甲氧苄啶-磺胺甲唑的耐药率较高,分别为96.4%、89.3%和67.4%;成人与儿童耐药情况基本一致。结论河北省内53所医院临床分离肺炎链球菌耐药情况总体与全国水平一致,但是仍有对个别抗菌药物耐药率增高。应警惕肺炎链球菌耐药菌株的出现,控制耐药菌的发生。
[Abstract]:Objective to investigate the drug resistance of Streptococcus pneumoniae isolated from 53 medical institutions in Hebei Province in 2015 and to provide support for rational drug use. Methods according to the requirements of bacterial drug resistance monitoring scheme, the clinical data of Streptococcus pneumoniae isolated from 53 member units of bacterial resistance monitoring network in Hebei Province were collected. According to CLSI 2014 standard, the data were analyzed by WHONET 5. 6. Results A total of 2 408 strains of Streptococcus pneumoniae were isolated. The sensitivities of isolated Streptococcus pneumoniae to vancomycin and moxifloxacin were 95%, while those to erythromycin, clindamycin, trimethoprim and sulfamethazol were 96.489. 3% and 67. 4%, respectively. The drug resistance of adults and children was basically the same. Conclusion the drug resistance of clinical isolates of Streptococcus pneumoniae in 53 hospitals in Hebei Province is consistent with the national level, but the rate of drug resistance to individual antibiotics is still increasing. We should guard against the emergence of resistant strains of Streptococcus pneumoniae and control the occurrence of resistant strains.
【作者单位】：秦皇岛市第一医院检验一科;河北医科大学第二医院检验科;河北省临床检验中心;河北医科大学第四医院检验科;承德医学院附属医院检验科;邢台市人民医院检验二科;河北大学附属医院检验科;华北理工大学;
【分类号】：R446.5

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