三维斑点追踪成像评价糖尿病患者心脏损害的Meta分析

发布时间：2018-04-27 14:52

本文选题：三维斑点追踪 + 糖尿病　；参考：《中国介入影像与治疗学》2017年02期

【摘要】：目的评价三维斑点追踪成像(3D-STI)定量测评糖尿病(DM)患者左心室应变的临床价值。方法计算机检索PubMed等数据库官方网站中2016年8月1日之前发表的有关3D-STI评价DM患者左心室功能的病例对照研究。确切的纳入与排除标准制定后,独立筛选文献、提取各项数据和评价质量分配给2名两名研究员。通过Stata 12.0软件分析权重均数差(WMD)及95%可信区间(CI)。结果最终纳入12篇病例对照研究,共计620例DM患者和473名正常者。Meta分析:DM组与对照组左心室射血分数的差异无统计学意义[WMD=-0.94,95%CI(-1.92,-0.04),P=0.06];左心室整体应变DM组与对照组相比差异均有统计学意义:径向应变[WMD=-3.63,95%CI(-5.15,-2.11),P0.01]、纵向应变[WMD=3.54,95%CI(2.71,4.36),P0.01]、环向应变[WMD 2.48,95%CI(1.49,3.48),P0.01]、面积应变[WMD=2.92,95%CI(2.33,3.50),P0.01)。结论 3D-STI定量测评糖尿病群体的左心室应变指标具有一定的临床价值。
[Abstract]:Objective to evaluate the clinical value of three-dimensional dot-tracking imaging (3D-STI) in quantitative assessment of left ventricular strain in patients with diabetes mellitus (DM). Methods A case control study on the evaluation of left ventricular function in DM patients by 3D-STI was published before Aug. 1, 2016 on the official website of PubMed and other databases. After the exact inclusion and exclusion criteria were established, the literature was independently screened, the data extracted and the quality evaluated assigned to two researchers. The weighted mean difference (WMD) and 95% confidence interval were analyzed by Stata 12.0 software. Results the results were included in 12 case-control studies. A Meta-analysis of 620 DM patients and 473 normal subjects. Meta-analysis showed that there was no significant difference in left ventricular ejection fraction between the two groups [WMD-0.94 ~ 95CI-1.92 ~ (-0.04) P0. 06], but there was a significant difference between the whole left ventricular strain group and the control group: radial strain [WMD-3.63CIT = -5.15 ~ (-2.11) P0.01], The circumferential strain [WMD 2.48-95], the area strain (WMD2.9295), the area strain (WMD2.9295CII / 2.33 / 3.50 / P0.01), the circumferential strain (WMD2.48-95CIQ), the area strain (WMD2.9295CII), the circumferential strain (WMD2.48-95CIQ), the area strain (WMD2.9295CII / 2.33 / 3.50 / P0.01). Conclusion quantitative assessment of left ventricular strain index by 3D-STI is of certain clinical value.
【作者单位】：重庆医科大学附属第二医院心血管内科;
【基金】：国家自然科学基金面上项目(81370440)
【分类号】：R445.1;R587.1

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