围绝经期妇女泌尿系统感染病原菌特点与耐药性研究

发布时间：2018-05-02 23:19

本文选题：围绝经期妇女 + 泌尿系统感染　；参考：《中华医院感染学杂志》2017年22期

【摘要】：目的探索围绝经期妇女泌尿系统感染病原菌种类与耐药性分析。方法选取2013年1月-2016年2月医院接受治疗的182例围绝经期泌尿系统感染患者为研究对象,取患者中段尿标本进行细菌培养,采用药敏纸片扩散法对病原菌进行筛选,并检测病原菌耐药性。结果 182例患者共检出病原菌159株,其中革兰阴性菌91株,革兰阳性菌36株,真菌32株;铜绿假单胞菌、肺炎克雷伯菌、大肠埃希菌以及奇异杆菌对四环素、氨苄西林、青霉素以及红霉素耐药性总体较高;革兰阳性菌中金黄色葡萄球菌、表皮葡萄球菌以及粪肠球菌对青霉素、红霉素、四环素、环丙沙星等抗菌药物耐药率最高;白假丝酵母、光滑假丝酵母等对青霉素、红霉素耐药性较高,而对如两性霉素、伊曲康唑、氟康唑等抗菌药物耐药率较低。结论围绝经期妇女泌尿系统感染病原菌种类以及构成较为复杂,病原菌对抗菌药物耐药性较高,临床上应该对病原菌构成进行准确检测。
[Abstract]:Objective to explore the types and drug resistance of pathogenic bacteria of urinary system infection in perimenopausal women. Methods 182 patients with urinary tract infection in perimenopausal period received hospital treatment from January 2013 to February 2016 were selected as the study objects. The bacteria were cultured in the middle urine samples of the patients, and the pathogens were screened by drug sensitive disk diffusion method. The drug resistance of pathogenic bacteria was detected. Results 159 strains of pathogenic bacteria were detected in 182 patients, including 91 Gram-negative bacteria, 36 Gram-positive bacteria, 32 fungi, Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli and Mycobacterium mirabilis to tetracycline, ampicillin, pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli and Mycobacterium mirabilis. Staphylococcus aureus, Staphylococcus epidermidis and Enterococcus faecalis were the most resistant to penicillin, erythromycin, tetracycline, ciprofloxacin, etc. Candida smoothing showed higher resistance to penicillin and erythromycin, but lower resistance to antimicrobial agents such as amphotericin, itraconazole and fluconazole. Conclusion the types and composition of pathogenic bacteria of urinary tract infection in menopausal women are more complicated, and the pathogens have higher resistance to antibiotics, so it is necessary to accurately detect the composition of pathogens in clinic.
【作者单位】：浙江省丽水市妇幼保健院妇科;
【分类号】：R446.5;R691.3

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