内耳前庭内淋巴体积测量在梅尼埃病中的应用研究

发布时间：2018-05-06 08:15

本文选题：梅尼埃病 + 前庭内淋巴　；参考：《广西医科大学》2017年硕士论文

【摘要】：目的:探讨内耳前庭内淋巴体积测量在梅尼埃病中的应用价值。方法:20例经临床确诊的梅尼埃病患者经鼓膜穿刺双侧鼓室内注入钆喷酸葡胺稀释液,24h后行MRI扫描,对内耳前庭内淋巴体积进行测量。10例为术前患者,其中7例为单侧发病患者,3例为双侧发病患者;10例为行单侧半规管填塞术后患者,其中8例为单侧发病患者,2例为双侧发病患者。采用配对t检验比较单侧发病术前患者患侧耳与健侧耳内耳前庭内淋巴体积、单侧发病术后患者术后耳与健侧耳内耳前庭内淋巴体积的差异;采用独立样本t检验比较术前患者患侧耳与术后患者术后耳内耳前庭内淋巴体积的差异。结果:7例单侧发病术前患者患侧耳和健侧耳内耳前庭内淋巴体积测量值分别为(11.67±3.63)mm3、(7.99±2.69)mm3,8例单侧发病术后患者术后耳和健侧耳内耳前庭内淋巴体积测量值分别为(7.54±2.55)mm3、(7.41±2.00)mm3,10例术前患者患侧耳与10例术后患者术后耳内耳前庭内淋巴体积测量值分别为(10.93±3.14)mm3、(7.46±2.26)mm3;单侧发病术前患者患侧耳和健侧耳内耳前庭内淋巴体积、术前患者患侧耳与术后患者术后耳内耳前庭内淋巴体积差异有统计学意义(P值0.05);单侧发病术后患者术后耳与健侧耳内耳前庭内淋巴体积差异无统计学意义(P值0.05)。结论:内耳前庭内淋巴体积测量能为临床诊断梅尼埃病提供影像学依据,同时为梅尼埃病的疗效评估提供有用的信息。
[Abstract]:Objective: to evaluate the value of intravestibular lymphatic volume measurement in Meniere's disease. Methods Twenty patients with Meniere's disease diagnosed by clinical diagnosis were treated with MRI scan after 24 hours of injection of meglumine gadolinium poumate diluted solution into the tympanic chamber through tympanic membrane puncture. The volume of the vestibular lymph nodes in the inner ear was measured in 10 patients before operation. Among them, 7 cases were unilateral, 3 cases were bilateral, 10 cases were treated with unilateral semicircular canal tamponade, 8 cases were unilateral and 2 cases were bilateral. T test was used to compare the volume of the vestibular lymphatic volume between the patients with unilateral preoperation and that of the patients with unilateral preoperation, and the volume of the vestibular lymphatic volume between the patients after unilateral onset and that of the patients after unilateral operation. T test was used to compare the volume of vestibular lymphoid volume between preoperatively and postoperatively patients with auricular vestibule. Results the volume measurements of the vestibular lymphatic volume in 7 cases of unilateral preoperation and 7 cases of healthy inner ear were 11.67 卤3.63 mm ~ (3), 7.99 卤2.69 mm ~ (3) and 7.54 卤2.55 mm ~ (3) and 7.41 卤2.00 mm ~ (3) ~ (-1), respectively, before and after operation of unilateral and internal ear of healthy lateral ear were 7.54 卤2.55 mm ~ (3) and 7.41 卤2.00 mm ~ (-1), respectively. The volume of vestibular lymphoid volume was 10.93 卤3.14 mm ~ (3) and 7.46 卤2.26 mm ~ (3) respectively in the patients with and 10 cases after operation, and the volume of the vestibular lymphoid volume of the affected and healthy ears was 7.46 卤2.26 mm ~ (3), respectively. There was significant difference in the volume of vestibular lymphatic volume between preoperation and postoperative patients, but there was no significant difference in the volume of vestibular lymph between unilateral and healthy ears. Conclusion: the measurement of intravestibular lymphatic volume of inner ear can provide imaging basis for clinical diagnosis of Meniere's disease and provide useful information for the evaluation of curative effect of Meniere's disease.
【学位授予单位】：广西医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R764.33;R445.2

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