磁共振功能成像在直肠癌T分期中的应用价值

发布时间：2018-05-10 22:38

本文选题：直肠肿瘤 + 磁共振功能成像　；参考：《实用医学杂志》2017年08期

【摘要】：目的:探讨磁共振功能成像方法扩散加权成像(DWI)和动态对比增强磁共振成像(DCE-MRI)在直肠癌T分期中的应用价值。方法:通过对78例经病理证实的直肠癌患者DWI及DCE-MRI图像进行回顾性分析,对比分析常规序列检查及磁共振功能成像联合常规序列检查T分期诊断差异,ADC值及DCE-MRI定量参数Ktrans、Ve、Kep值与肿瘤的T分期的相关性。结果:磁共振功能成像联合常规序列检查T分期正确68例、准确率87.2%对直肠癌术前T分期与术后病理的一致性优于常规序列检查T分期正确59例,准确率75.6%(Kappa值0.81 vs 0.65,P0.05);ADC值及DCE-MRI定量参数Ktrans、Ve值随肿瘤T分期的增加(均P0.05);Kep值差异无统计学意义。结论:ADC值及DCE-MRI定量参数Ktrans、Ve值与直肠癌的T分期存在一定的相关性,磁共振功能成像能有效提高直肠癌术前T分期的准确率,对判断肿瘤在直肠壁的浸润深度具有一定的临床应用价值。
[Abstract]:Objective: to evaluate the value of diffusion weighted Mr imaging (DWI) and dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) in T staging of rectal cancer. Methods: the DWI and DCE-MRI images of 78 patients with rectal cancer confirmed by pathology were analyzed retrospectively. The difference of T staging between conventional sequence and Mr functional imaging combined with conventional sequence was compared. The correlation between ADC value and DCE-MRI quantitative parameter (KTrans-Veep) and T stage of tumor was analyzed. Results: MRI combined with conventional sequence was correct in 68 patients with T staging. The accuracy rate of T staging was 87.2%, which was superior to that of conventional sequence examination in 59 cases, and the consistency of preoperative T staging with postoperative pathology was superior to that of conventional sequence. The accuracy rate of 75.6%(Kappa value 0.81 vs 0.65% P0.05A value and DCE-MRI quantitative parameter KtransV value increased with T stage of the tumor (all P 0.05) and there was no significant difference between them. Conclusion there is a certain correlation between the ratio of% ADC and KtransVe, the quantitative parameter of DCE-MRI, and the T staging of rectal cancer. Magnetic resonance functional imaging can effectively improve the accuracy of preoperative T staging of rectal cancer. It has certain clinical application value in judging the depth of tumor invasion in rectal wall.
【作者单位】：华北理工大学附属医院磁共振室;
【基金】：河北省科技计划项目(编号:162777139)
【分类号】：R445.2;R735.37

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