多项指标联合检测对结核性胸膜炎的诊断价值

发布时间：2018-05-12 02:09

  本文选题：结核性胸膜炎 + 腺苷脱氨酶　； 参考：《医学理论与实践》2017年09期

【摘要】：目的:评价腺苷脱氨酶(ADA)、结核抗体(TB-Ab)以及结核分枝杆菌DNA(TB-DNA)联合检测在结核性胸膜炎的诊断价值。方法:分别检测病例组(82例结核性胸膜炎患者)和对照组(80例非结核性胸膜炎患者)胸水中ADA、TB-Ab和TB-DNA指标阳性率,对单一和联合检测结果进行评价。结果:病例组患者ADA、TB-Ab以及TBDNA阳性率均高于对照组,差异有统计学意义(P0.05);ADA、TB-Ab和TB-DNA联合检测的诊断价值最高,灵敏度为87.80%,特异度为83.75%,约登指数为0.716,阳性预测值为84.71%,阴性预测值为87.01%。结论:ADA、TB-Ab和TB-DNA在结核性胸膜炎患者中的阳性率较高,并且三指标联合检测对结核性胸膜炎具有较高的诊断价值,有助于早期诊断。
[Abstract]:Objective: to evaluate the diagnostic value of adenosine deaminase ADAA, TB antibody TB-Aband Mycobacterium tuberculosis DNA TB-DNA in the diagnosis of tuberculous pleurisy. Methods: the positive rates of ADA-TB-Ab and TB-DNA in pleural effusion of 82 patients with tuberculous pleurisy and 80 patients with non-tuberculous pleurisy in the control group were detected, and the results of single and combined detection were evaluated. Results: the positive rates of ADA-TB-Ab and TBDNA in the case group were higher than those in the control group. The difference was statistically significant (P 0.05). The diagnostic value of TB-Ab combined with TB-DNA was the highest, the sensitivity was 87.80, the specificity was 83.755.The Yorden index was 0.716, the positive predictive value was 84.71, and the negative predictive value was 87.01. Conclusion the positive rate of TB-Ab and TB-DNA in tuberculous pleurisy is higher than that of TB-Ab in tuberculous pleurisy, and the combined detection of three indexes has high diagnostic value for tuberculous pleurisy, which is helpful to the early diagnosis of tuberculous pleurisy.
【作者单位】： 河南省郑州市第六人民医院检验科;
【分类号】：R446.5;R521.7
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本文编号：1876637