超声造影评价特殊部位肝癌微波消融联合补充无水乙醇治疗的应用价值

发布时间：2018-05-15 09:55

本文选题：超声造影 + 微波消融　；参考：《中国超声医学杂志》2017年03期

【摘要】：目的探讨超声造影实时动态观察特殊部位肝癌微波消融联合无水乙醇治疗的应用价值。方法对45例特殊部位肝癌患者,共73个病灶,分为两组对比观察:微波消融组(A组)和微波消融+无水乙醇联合治疗组(B组)。A组共32个,其中邻近大血管或胆管处6个,靠近膈肌或肝包膜处16个,邻近周围重要器官处10个;B组共41个,其中邻近大血管或胆管处9个,靠近膈肌或肝包膜处19个,邻近周围重要器官处13个;每组分别行超声造影检查,同期行增强MRI进行比较。结果 (1)超声造影检查发现A组完全消融22个,未完全消融10个,完全消融率为68%;B组完全消融37个,未完全消融4个,完全消融率为90%。(2)增强MRI检查发现A组完全消融20个,未完全消融12个,完全消融率为62%;B组完全消融35个,未完全消融6个,完全消融率为85%。(3)A组与B组分布部位差异无统计学意义(P0.05),超声造影发现B组疗效优于A组,差异有统计学意义(P0.05);超声造影与增强MRI间比较差异无统计学意义(P0.05)。结论微波消融联合无水乙醇治疗特殊部位肝癌有较好的疗效,超声造影能实时动态观察肝癌血流灌注情况,对特殊部位肝癌治疗有重要的临床指导意义。
[Abstract]:Objective to investigate the value of real-time dynamic observation of microwave ablation combined with anhydrous alcohol therapy for hepatocellular carcinoma in special site. Methods Forty-five patients with liver cancer with special site were divided into two groups: microwave ablation group (group A) and microwave ablation group (group B). There were 32 cases in group A (adjacent to large vessels or bile duct) and 32 cases in group A (group B) treated with microwave ablation of anhydrous alcohol. There were 16 cases near the diaphragm or hepatic capsule, and 41 in group B in 10 adjacent important organs, including 9 near the great vessels or bile ducts, 19 near the diaphragm or hepatic capsule, and 13 adjacent to the surrounding important organs. Contrast-enhanced ultrasonography was performed in each group and contrast-enhanced MRI was performed at the same time. Results (1) Twenty-two complete ablation, 10 incomplete ablation, 37 complete ablation, 4 incomplete ablation, and 90% complete ablation rate were found in group A by contrast-enhanced MRI. 20 patients in group A were completely ablated by contrast-enhanced MRI, and the total ablation rate was 37 in group B, 4 in group B, and the rate of complete ablation was 90.2.Contrast-enhanced MRI showed that 20 patients in group A were completely ablated. There were 12 incomplete ablation, 35 complete ablation and 6 incomplete ablation in group B. There was no significant difference between group A and group B. contrast-enhanced ultrasonography showed that the curative effect of group B was better than that of group A. The difference was statistically significant (P 0.05), but there was no significant difference between contrast-enhanced MRI and contrast-enhanced ultrasonography (P 0.05). Conclusion Microwave ablation combined with anhydrous ethanol is effective in the treatment of hepatocellular carcinoma in special sites. Contrast-enhanced ultrasound can observe the blood flow of HCC in real time and dynamically, and has important clinical guiding significance for the treatment of HCC in special sites.
【作者单位】：武汉科技大学附属天佑医院超声医学科;
【分类号】：R445.1;R735.7

【相似文献】