IVIM-DWI评价高强度聚焦超声治疗子宫肌瘤早期疗效的价值

发布时间：2018-06-04 22:12

  本文选题：体素内不相干运动 + 高强度聚焦超声　； 参考：《临床放射学杂志》2017年05期

【摘要】：目的探讨体素内不相干运动扩散加权成像(IVIM-DWI)评价高强度聚焦超声(HIFU)治疗子宫肌瘤早期疗效应用价值。方法回顾性分析HIFU治疗的15个子宫肌瘤患者资料,治疗前、1天后均行增强MRI(CEMRI)及IVIM-DWI检查,IIVIM-DWI采用16个b值,利用软件计算出D值、D*值及f值,并且获取各参数值图,采用独立样本t检验比较子宫肌瘤消融区域与术前瘤体及消融灶邻近组织间各值的差异。结果子宫肌瘤的D值、D*值及f值分别为(0.79±0.10)×10~(-3)mm~2/s、(19.87±2.12)×10~(-3)mm~2/s及(25.2±2.7)%,子宫肌瘤消融区域的D值、D*值及f值分别为(1.37±0.45)×10~(-3)mm~2/s、(3.13±0.21)×10~(-3)mm~2/s及(9.5±0.7)%,消融灶邻近组织D值、D*值及f值分别为(1.32±0.13)×10~(-3)mm~2/s、(3.99±0.11)×10~(-3)mm~2/s及(20.6±1.1)%。子宫肌瘤消融区域D值较术前明显升高,两者之间有统计学差异(P0.05),D*值、f值较术前明显减低,两者之间有统计学差异(P0.05),D*值、f值较消融灶邻近组织减低,两者之间有统计学差异(P0.05),D值无统计学差异。子宫肌瘤消融区域D*值及f值ROC曲线下面积分别为0.902、0.952,敏感度分别为92.8%、97.8%,特异度分别为61.2%、68.2%。结论IVIM-DWI的D*值、f值对子宫肌瘤HIFU术后疗效评价具有重要的价值,f值效果较佳。
[Abstract]:Objective to evaluate the early efficacy of high intensity focused ultrasound (HIFU) in the treatment of uterine leiomyoma by IVIM-DWI. Methods the data of 15 patients with uterine leiomyoma treated with HIFU were retrospectively analyzed. Before and one day after treatment, enhanced MRI CE MRI) and IVIM-DWI examination were performed with 16 b values on IIVIM-DWI. The D value D * and f value were calculated by software, and all parameter maps were obtained. T test was used to compare the difference between the ablation area of uterine leiomyoma and the preoperative tumor and adjacent tissue. 缁撴灉瀛愬��鑲岀槫鐨凞鍊，

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