动态增强磁共振与扩散张量成像对前列腺中央区良恶性结节的诊断价值

发布时间：2018-06-05 13:41

本文选题：前列腺肿瘤 + 磁共振成像　；参考：《中国医学影像学杂志》2017年07期

【摘要】：目的研究动态增强磁共振扫描(DCE-MRI)、扩散张量成像(DTI)及两者联合对前列腺中央区良恶性结节的诊断价值。资料与方法回顾性分析2015年9月-2016年12月在石河子大学医学院第一附属医院行前列腺MRI扫描的49例前列腺中央区有结节样异常信号患者,均行磁共振T2WI、DTI及DCE扫描。经病理学证实,57例中央区结节样本中21例为前列腺癌(PCa)、36例为良性前列腺增生(BPH)。分别测量结节的各向异性分数值、表观扩散系数值、峰值时间、强化率、曲线斜率值,描述时间-信号强度曲线,比较各参数在PCa与BPH之间的差异,并进行受试者工作特性(ROC)曲线分析。结果 PCa组与BPH组的各向异性分数值、表观扩散系数值、峰值时间、曲线斜率值差异均有统计学意义(P0.05),强化率组间差异无统计学意义(P0.05);PCa的时间-信号强度曲线类型以速升下降型为主,BPH曲线类型以平台型为主。DCE、DTI及两者联合诊断的ROC曲线下面积分别为0.87(95%CI:0.751~0.942)、0.85(95%CI:0.734~0.933)和0.94(95%CI:0.837~0.983)。结论与DTI及DCE分别诊断前列腺中央区良恶性结节相比,两者联合诊断具有更高的准确性。
[Abstract]:Objective to study the diagnostic value of dynamic contrast enhanced magnetic resonance imaging (DCE-MRI), diffusion Zhang Liang imaging (Zhang Liang) and their combination in benign and malignant nodules in the central region of prostate. Materials and methods 49 patients with nodular abnormal signal in the central region of prostate underwent MRI scan in the first affiliated Hospital of Shihezi University School of Medicine from September 2015 to December 2016. All patients underwent T2WI DTI and DCE scans. Among the 57 cases of central nodule confirmed by pathology, 21 cases were diagnosed as prostate cancer and 36 cases were benign prostatic hyperplasia (BPH). The anisotropic fraction, apparent diffusion coefficient, peak time, enhancement rate and curve slope of the nodules were measured. The time-signal intensity curves were described, and the differences of the parameters between PCa and BPH were compared. The operating characteristics of the subjects were analyzed. Results the anisotropic fraction, apparent diffusion coefficient and peak time of PCa and BPH groups were measured. There were significant differences in slope value of curve between two groups (P 0.05). There was no significant difference in enhancement rate between groups. The time-signal intensity curve type of P0.05A was mainly rapid rising and decreasing type. DCE-DTI was mainly platform type. DCE-DTI and ROC diagnosed by both methods were not statistically significant. The areas under the curve were 0.870.751and 0.9420.8595, respectively. Conclusion compared with DTI and DCE, the combined diagnosis of benign and malignant nodules in the central region of prostate is more accurate.
【作者单位】：石河子大学医学院第一附属医院MR室;西南医科大学附属医院放射科;
【分类号】：R445.2;R737.25

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