悬浮红细胞储存时间对妇科患者输血不良反应的影响

发布时间：2018-06-17 23:50

本文选题：输血不良反应 + 非溶血性发热反应　；参考：《中国输血杂志》2017年08期

【摘要】：目的研究悬浮红细胞储存时间对妇科患者输血不良反应的影响。方法选取本院妇科住院输注悬浮红细胞的患者,将患者输注红细胞储存时间均≤14 d者纳入新鲜组,输注红细胞储存时间均14 d者纳入陈旧组,分析2组患者输血后不良反应的发生率及输血后血液相关指标的差异。结果陈旧组不良反应率(2.45%),新鲜组不良反应率(1.32%),差异有统计学意义;陈旧组非溶血性发热反应率(1.42%),新鲜组非溶血性发热反应率(0.66%),差异有统计学意义;陈旧组过敏性输血反应率(1.03%),新鲜组过敏性输血反应率(0.66%),差异无统计学意义。输血后2组的电解质、血凝分析指标差异无统计学意义,陈旧组总胆红素明显高于新鲜组,差异有统计学意义。结论悬浮红细胞的储存时间对于妇科患者的输血不良反应发生有明显影响:输入储存时间长的悬浮红细胞(14 d)使得患者更容易发生FNHTR,输入储存时间长的悬浮红细胞(14 d)会增加患者溶血的风险并降低红细胞输注效果。
[Abstract]:Objective to study the effect of storage time of suspended red blood cell on adverse reaction of blood transfusion in gynecological patients. Methods the patients with suspended red blood cell transfusion in our hospital were included in the fresh group and the old group in which the storage time of the red blood cell was less than 14 days, and the storage time of the infused red blood cell was 14 days. The incidence of adverse reactions after blood transfusion and the differences of blood related indexes between the two groups were analyzed. Results the adverse reaction rate of the old group was 2.45%, the rate of the fresh group was 1.322.The rate of non-hemolytic fever in the old group was 1.42%, and the rate of non-hemolytic fever reaction in the fresh group was 0.66 (P < 0.05). The anaphylactic blood transfusion reaction rate was 1.03 in the old group and 0.66 in the fresh group. There was no significant difference in electrolytes and hemagglutination between the two groups after blood transfusion. The total bilirubin in the old group was significantly higher than that in the fresh group, and the difference was statistically significant. Conclusion the storage time of suspended red blood cells has a significant effect on the occurrence of adverse reactions of blood transfusion in gynecological patients: the patients are more likely to develop FNHTR, and the patients are more likely to develop FNHTR, and the longer storage time is imported into the suspended red blood cells for 14 days. Cytosol 14 d) increased the risk of hemolysis and reduced the effect of erythrocyte transfusion.
【作者单位】：郑州大学第三附属医院输血科;
【分类号】：R457.1;R71

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