1例高压氧联合间充质干细胞治疗局部Ⅲ度放射损伤病人的护理

发布时间：2018-06-29 12:14

本文选题：放射损伤 + 间充质干细胞　；参考：《护理研究》2017年10期

【摘要】：[目的]总结1例颜面部Ⅱ度、指端Ⅲ度意外放射损伤病人的护理体会。[方法]建立单间保护性隔离病房,观察照射部位皮肤变化,指端过氧化氢清创、碘伏消毒,然后指端局部皮肤注射骨髓间充质干细胞(MSC),并给予二甲基亚砜外敷及复方氨基酸脂质体外涂;颜面部给予生理盐水清创后间充质干细胞上清液湿敷,重组牛碱性成纤维细胞生长因子眼用凝胶外涂等处理,全身应用抗生素预防感染,高压氧治疗修复受损组织细胞。[结果]病人颜面部皮肤未形成溃疡;右手指水疱破溃结痂,痂皮脱落后瘢痕愈合良好,仅指尖局部溃疡未愈合,转至整形外科行清创+皮片移植修复术。[结论]高压氧治疗及间充质干细胞局部注射可促进急性放射性皮肤损伤后皮肤组织的修复和再生。
[Abstract]:[Objective] to sum up the nursing experience of 1 cases with degree II of the face and finger tip III degree accidental radiation injury. [Methods] a single protective isolation ward was established to observe the skin changes of the irradiated area, the finger end hydrogen peroxide debridement and iodophor disinfection, and then the local skin injection of bone marrow mesenchymal stem cells (MSC) on the fingertip, and the external application of methyl sulfoxide and compound ammonia were given. Liposomes were coated in vitro; facial skin was treated with wet compress of supernatant of mesenchymal stem cells after debridement of normal saline, recombinant bovine basic fibroblast growth factor ophthalmic gel was applied, antibiotics were used to prevent infection, and hyperbaric oxygen was used to repair damaged tissue cells. [results] the skin of the face of the sick person did not form ulcers, and the right finger bullblain was broken. The scars healed well and the scars were healed well, only the local ulcers were not healed and transferred to plastic surgery. [Conclusion] hyperbaric oxygen therapy and local injection of mesenchymal stem cells could promote the repair and rebirth of skin tissue after acute radiation skin injury.
【作者单位】：中国人民解放军第三0七医院;
【分类号】：R473

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