乳腺癌化疗患者的人格和心理健康变化及其与癌因性疲乏的相关性分析

发布时间：2018-08-23 09:35

【摘要】：目的研究乳腺癌化疗后患者的人格和生活质量变化以及与癌因性疲乏相关性。方法研究对象选取上海市肿瘤医院和中山医院2013年12月到2014年7月间接受化疗治疗的乳腺癌患者66例,应用横断面调查方法,采用一般资料问卷、癌因性疲乏量表(CFS)、症状自评量表(SCL-90)及艾森克人格问卷简式量表(EPQ-RSC)对患者进行调查,分析化疗对患者的CFS、SCL-90及EPQ-RSC评分影响,并用Spearman相关分析其相关性。结果所有患者的疲乏总分为(35.45±7.21)分,处于中度水平;神经质和精神质评分均名高于国内常模标准得分(P0.05);化疗后所有患者的SCL-90总分和各因子得分均明显高于化疗前(P0.01);神经质与疲乏总分、躯体疲乏、心理疲乏、认知疲乏均存在显著正相关(P0.01),与SCL-90总分、抑郁、焦虑和恐怖因子呈正相关(P0.01);精神质与情感疲乏存在显著正相关(P0.01);内-外向性与疲乏总分、心理疲乏均存在显著负相关(P0.01),与抑郁、焦虑和恐怖因子呈负相关(P0.01)。结论癌因性疲乏较普遍存在于乳腺癌化疗患者,化疗在一定程度上危害患者心理健康。癌因性疲乏可能受人格因素影响,而心理健康与人格也可能存在一定相关性。
[Abstract]:Objective to study the changes of personality and quality of life (QOL) in patients with breast cancer after chemotherapy. Methods 66 patients with breast cancer treated by indirect chemotherapy from December 2013 to July 2014 were selected from Shanghai Cancer Hospital and Zhongshan Hospital. The patients were investigated by (CFS), symptom Checklist (SCL-90) and Eysenck Personality questionnaire (EPQ-RSC). The effects of chemotherapy on CFSS-SCL-90 and EPQ-RSC scores were analyzed. The correlation between SCL-90 and EPQ-RSC was analyzed by Spearman correlation. Results the total score of fatigue in all patients was (35.45 卤7.21), which was at the moderate level. The scores of neuroticism and psychoticism were higher than those of the national norm (P0.05); the total score of SCL-90 and the scores of all factors after chemotherapy were significantly higher than those before chemotherapy (P0.01); the total scores of neuroticism and fatigue, somatic fatigue, psychological fatigue were significantly higher than those before chemotherapy (P0.01). There was a significant positive correlation between cognitive fatigue and SCL-90, depression, anxiety and phobic factors (P0.01), significant positive correlation between psychoticism and affective fatigue (P0.01), significant negative correlation between introverse-extroversion and total score of fatigue, psychological fatigue (P0.01), and significant negative correlation between mental fatigue and depression (P0.01). There was a negative correlation between anxiety and phobic factors (P0.01). Conclusion Carcinomatous fatigue is common in patients with breast cancer and chemotherapy is harmful to their mental health to some extent. Cancer-related fatigue may be influenced by personality factors, and mental health may be related to personality.
【作者单位】：上海市交通大学医学院附属精神卫生中心;
【分类号】：R473.73

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