钆贝葡胺磁共振成像对肝细胞癌的诊断价值

发布时间：2018-08-24 16:18

【摘要】：目的:探讨钆贝葡胺(Gd-BOPTA)一站式双功能对比MR成像(DFCE-MRI)对于肝细胞癌(HCC)诊断的价值。方法:对117例肝脏局灶性病变(FLL)患者行Gd-BOPTA一站式DFCE-MRI,包括:(1)MR平扫;(2)弥散加权成像(DWI);(3)Gd-BOPTA多期增强;(4)肝胆期扫描,比较Ⅰ((1))、Ⅱ((1)+(3))、Ⅲ((1)+(2)+(3))、Ⅳ((1)+(2)+(3)+(4),即:一站式DFCE-MRI)等四种扫描方案对于FLL的检出率和对HCC诊断的敏感性、特异性、准确性。结果:Ⅰ~Ⅳ四种扫描方案对FLL检出率分别为74.2%、87.4%、98.7%和98.7%,四者差异有统计学意义(P0.05),方案Ⅰ检出率明显低于其他三种增强扫描方案;Ⅱ~Ⅳ三种增强扫描方案对HCC诊断的敏感度、特异度、准确度分别为76.2%、70.1%和73.1%,92.9%、82.9%和85.5%,92.9%、90.5%和91.2%,三者差异有统计学意义(P0.05),且以方案Ⅳ准确度最高。结论:Gd-BOPTA一站式DFCE-MRI对FLL检出率以及对HCC诊断的准确度优于其他扫描方案,可以作为肝细胞癌鉴别诊断的优选MR扫描方案。
[Abstract]:Objective: to evaluate the value of gadolinium meglumine (Gd-BOPTA) one-stop dual-function contrast MR imaging (DFCE-MRI) in the diagnosis of hepatocellular carcinoma (HCC). Methods: one stop Gd-BOPTA DFCE-MRI, was performed in 117 patients with focal hepatic lesions (FLL) including: (1) MR plain scan; (2) diffusion-weighted (DWI); (3) Gd-BOPTA multiphase enhancement; (4) hepatobiliary phase scan. The detection rate of FLL and the sensitivity, specificity and accuracy of four scanning protocols 鈪，

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