综合ICU患者贫血现况调查及原因分析
发布时间:2018-11-01 10:40
【摘要】:目的:对综合ICU患者贫血的现况进行描述,了解非失血性脓毒症患者血红蛋白的变化过程及可能的原因。方法:收集宁夏医科大学总医院2015年1月1日至12月31日所有收住ICU的患者,经排除标准筛选后,对ICU患者的血红蛋白及标本采集失血量进行回顾性分析。记录患者的一般资料、入院诊断、入科基础血红蛋白(Hb)数值、入ICU 24小时内急性生理学及慢性健康评分(APACHEⅡ评分)及序贯器官衰竭估计评分(SOFA评分)、ICU期间血红蛋白(Hb)水平、住院天数、标本采集失血量,得出入科患者贫血发生的情况,并排除显性失血量大于50ml的患者,将患者病情按脓毒症及非脓毒症进行分组,分别了解其血红蛋白的变化情况。结果:宁夏医科大学总医院2015年1月1日至12月31日共收治患者794例,251例患者符合纳入标准。在ICU住院期间贫血发生率为58%,患者血红蛋白平均下降2.41±4.25g/L/day。对于210例住ICU时间大于2天的患者,前2天血红蛋白下降程度大于后续时间,前2天血红蛋白变化为:7.8±12.2g/L/day,两天后血红蛋白变化为:2.3±14.1g/L/day(P0.01)。对于住院时间大于两天的患者,后续住院时间的日均血红蛋白下降水平与APACHE II评分及SOFA评分呈正相关(P=0.00、P=0.00)。251例入选患者入科后接受抽血次数为22.43±16.85次,平均每天采血数量为4.16±1.71管,总采血量为74.45±45.90ml,脓毒症患者112人,平均每天采血数量为4.58±1.98管,采血总量为100.24±55.54ml,非脓毒症患者139人,平均每天采血量为3.83±1.37管,采总血量为53.52±40.85ml。251例入选患者,除外创伤性失血、术中失血、消化道出血量大于50ml的患者,共57例入选,其中脓毒症患者36例,非脓毒症患者21例,脓毒症患者血红蛋白下降为2.31±2.56g/L/day,非脓毒症患者血红蛋白下降为0.92±2.34g/L/day(P=0.04),对于住院时间大于2天的患者,前2天脓毒症患者血红蛋白下降8.28±12.92g/L,非脓毒症患者血红蛋白下降3.86±12.09g/L(P=0.30),2天后脓毒症患者组血红蛋白持续下降,而非脓毒症患者组血红蛋白无明显下降(9.28±11.39 VS 1.25±6.68g/L P=0.03)。结论:1、宁医大总院ICU患者入院第二天血红蛋白下降最显著。2、脓毒症患者血红蛋白下降原因考虑与疾病本身严重程度及静脉采血量有关。
[Abstract]:Objective: to describe the current status of anemia in patients with ICU and to understand the process and possible causes of hemoglobin changes in patients with non-hemorrhagic sepsis. Methods: all the patients with ICU were collected from January 1 to December 31, 2015 in Ningxia Medical University General Hospital. The hemoglobin and blood loss of ICU patients were analyzed retrospectively. The general data, admission diagnosis, basic hemoglobin (Hb) value, acute physiology and chronic health score (APACHE 鈪,
本文编号:2303665
[Abstract]:Objective: to describe the current status of anemia in patients with ICU and to understand the process and possible causes of hemoglobin changes in patients with non-hemorrhagic sepsis. Methods: all the patients with ICU were collected from January 1 to December 31, 2015 in Ningxia Medical University General Hospital. The hemoglobin and blood loss of ICU patients were analyzed retrospectively. The general data, admission diagnosis, basic hemoglobin (Hb) value, acute physiology and chronic health score (APACHE 鈪,
本文编号:2303665
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