食物不耐受相关性赋能教育对溃疡性结肠炎患者的效果研究

发布时间：2018-11-12 16:06

【摘要】：目的研究食物不耐受相关性赋能教育对溃疡性结肠炎(UC)患者的干预效果,为临床指导提供依据。方法选取2013年9月—2014年8月在天津医科大学总医院住院的UC患者89例,根据其接受食物不耐受相关性赋能教育的意愿分为试验组(n=47)和对照组(n=42)。试验组患者接受面对面的食物不耐受相关性赋能教育,对照组接受传统电话随访健康教育,1次/2周,持续干预6个月。采用酶联免疫吸附试验(ELISA)检测患者食物不耐受情况;并于干预前及干预6个月后采用简明健康状况调查问卷(SF-36)评估患者生活质量;测量体质指数(BMI)及血清总蛋白(TP)、清蛋白(ALB)、前清蛋白(PA)、转铁蛋白(TRF)水平评估患者营养状况;采用Southerland疾病活动指数(DAI)评分系统评估患者疾病活动程度。结果 89例UC患者食物不耐受阳性率为67.4%(60/89)。试验组患者食物不耐受阴性14例,轻度不耐受6例,中度不耐受1例,重度不耐受26例;对照组患者分别为15、4、1、22例,两组食物不耐受发生情况比较,差异无统计学意义(Z=0.416,P=0.677)。干预前,两组SF-36各维度得分比较,差异均无统计学意义(P0.05);干预后,试验组躯体职能、总体健康、社会功能、情感职能、心理卫生得分均高于对照组以及同组干预前(P0.05)。干预前,两组患者BMI、TP、ALB、PA、TRF水平比较,差异均无统计学意义(P0.05);干预后,试验组ALB水平高于对照组和同组干预前(P0.05)。干预前,两组Southerland DAI评分比较,差异无统计学意义(t=0.219,P=0.827);干预后,试验组Southerland DAI评分低于对照组(t=2.726,P=0.008)。结论对UC患者进行食物不耐受相关性赋能教育可以提高患者生活质量及营养状况,改善疾病预后。
[Abstract]:Objective to study the effect of food intolerance related enabling education on ulcerative colitis patients with (UC). Methods Eighty-nine UC patients admitted to Tianjin Medical University General Hospital from September 2013 to August 2014 were randomly divided into two groups according to their willingness to receive education related to food intolerance: experimental group (n = 47) and control group (n = 42). Patients in the trial group received face-to-face education on food intolerance related enabling education while the control group received health education by traditional telephone follow-up once a week for 6 months. The food intolerance was detected by Elisa (ELISA), and the quality of life was evaluated by SF-36 before and 6 months after intervention. Body mass index (BMI) and serum total protein (TP), albumin (ALB), prealbumin (PA), transferrin (TRF) were measured to evaluate the nutritional status of the patients. The disease activity degree of patients was evaluated by Southerland disease activity index (DAI) score system. Results the positive rate of food intolerance in 89 UC patients was 67.4% (60 / 89). There were 14 cases of negative food intolerance, 6 cases of mild intolerance, 1 case of moderate intolerance and 26 cases of severe intolerance. The incidence of food intolerance was not significantly different between the control group and the control group (P 0. 677, P 0. 677). Before intervention, there was no significant difference in the scores of SF-36 between the two groups (P0.05). After intervention, the scores of somatic function, general health, social function, emotional function and mental health in the experimental group were higher than those in the control group and before intervention (P0.05). Before intervention, there was no significant difference in BMI,TP,ALB,PA,TRF levels between the two groups (P0.05); after intervention, the ALB level of the experimental group was higher than that of the control group and the same group before intervention (P0.05). Before intervention, there was no significant difference in Southerland DAI score between the two groups (t = 0.219), but after intervention, the Southerland DAI score in the trial group was lower than that in the control group (t = 2.726). Conclusion Food intolerance related education can improve the quality of life and nutritional status and improve the prognosis of UC patients.
【作者单位】：天津医科大学总医院普外科;天津医科大学总医院护理部;
【基金】：黎介寿院士肠道屏障研究专项基金资助项目(LJS_201008)
【分类号】：R473.5

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