焦作市某医院228株肠球菌的临床分布及耐药性分析

发布时间：2018-12-13 05:53

【摘要】：目的分析某院228株肠球菌的临床分布及耐药状况,为临床合理使用抗生素提供依据。方法对该院228株肠球菌进行回顾性分析,采用珠海黑马微生物鉴定产品进行细菌鉴定及药敏试验,应用WHONET 5.6软件对数据进行分析处理。结果经细菌鉴定仪鉴定,所分离228株肠球菌中粪肠球菌125株(54.82%);屎肠球菌97株(42.54%);鸟肠球菌3株(1.32%);鹑鸡肠球菌2株(0.88%);铅黄肠球菌1株(0.44%)。以尿标本和伤口分泌物居多,分别占61.84%(141株)和16.67%(38株)。未检出对万古霉素、替考拉宁、利奈唑胺、替加环素耐药的粪肠球菌和屎肠球菌,鹑鸡肠球菌、铅黄肠球菌对万古霉素天然耐药,其余抗菌药物呈现不同程度耐药性。结论肠球菌主要引起人类泌尿系统感染,不同种类肠球菌对药物敏感性差别较大。临床应根据肠球菌鉴定及药敏合理使用抗生素,以减少耐药菌的增加。
[Abstract]:Objective to analyze the clinical distribution and drug resistance of 228 strains of Enterococcus in a hospital. Methods A retrospective analysis of 228 strains of Enterococcus was carried out in this hospital. The bacterial identification and drug sensitivity test were carried out by using the microbiological identification products of Zhuhai Black Horse. The data were analyzed and processed by WHONET 5.6 software. Results among 228 strains of Enterococcus faecalis, 125 strains (54.82%), 97 strains (42.54%), 3 strains (1.32%), 2 strains (0.88%) of Enterococcus faecium were identified by bacterial identification instrument. 1 strain (0.44%) of Enterococcus lead. Urine samples and wound secretions accounted for 61.84% (141 strains) and 16.67% (38 strains) respectively. No vancomycin, teicoplanin, linazolamine, tegicycline resistant Enterococcus faecalis and fecal Enterococcus, Enterococcus quail and Enterococcus lead were naturally resistant to vancomycin, and other antimicrobial agents showed resistance to vancomycin to varying degrees. Conclusion Enterococcus mainly causes human urinary tract infection, and the drug sensitivity of different strains of Enterococcus is different. In order to reduce the increase of resistant bacteria, antibiotics should be used rationally according to the identification of Enterococcus and drug sensitivity.
【作者单位】：焦作市第五人民医院检验科;宁夏医科大学临床医学院医学检验系;盐城市第六人民医院检验科;襄阳职业技术学院医学院;深圳市龙华新区人民医院检验科;
【基金】：宁夏临床病原微生物重点实验室开放课题(2015,LCPM201502-1) 2015年宁夏研究生教育创新计划项目,项目编号:NXYC201511
【分类号】：R446.5

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