参附注射液治疗老年多器官功能障碍综合征的临床观察

发布时间：2019-06-21 05:34

【摘要】：目的研究参附注射液治疗老年多器官功能障碍综合征(multiple organ dysfunction syndrome in the elderly,MODSE)患者的临床应用效果。方法将2014年2月—2016年3月诊治的100例MODSE患者,按治疗方法分为对照组(50例)和观察组(50例)。两组患者均进行常规西医治疗,观察组则在此基础上联合参附注射液治疗。对比两组的临床疗效,并对治疗前后慢性健康状况评分系统Ⅲ(APACHEⅢ)评分和血清肿瘤坏死因子-α(TNF-α)水平进行对比分析。结果观察组治疗总有效率高于对照组(P0.05)。观察组治疗后APACHEⅢ评分和血清TNF-α水平均明显低于对照组和治疗前(P0.05)。观察组不良反应发生率明显低于对照组(P0.05)。结论在常规西医治疗基础上联合参附注射液治疗MODSE具有显著效果。
[Abstract]:Objective to study the clinical effect of Shenfu injection in the treatment of elderly patients with multiple organ dysfunction syndrome (multiple organ dysfunction syndrome in the elderly,MODSE). Methods from February 2014 to March 2016, 100 patients with MODSE were divided into control group (n = 50) and observation group (n = 50). Both groups were treated with routine western medicine, while the observation group was treated with Shenfu injection. The clinical efficacy of the two groups was compared, and the scores of chronic health status scoring system III (Apache III) and the level of serum tumor necrosis factor-伪 (TNF- 伪) were compared and analyzed before and after treatment. Results the total effective rate of treatment in the observation group was higher than that in the control group (P 0.05). The Apache III score and serum TNF- 伪 level in the observation group were significantly lower than those in the control group and before treatment (P 0.05). The incidence of adverse reactions in the observation group was significantly lower than that in the control group (P 0.05). Conclusion on the basis of routine western medicine treatment, Shenfu injection is effective in the treatment of MODSE.
【作者单位】：天门市第一人民医院ICU;天门市妇幼保健院妇产科;
【基金】：湖北省自然科学基金项目(993137)
【分类号】：R459.7

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