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慢性阻塞性肺疾病患者执行功能障碍的危险因素分析

发布时间:2019-06-21 11:38
【摘要】:目的分析慢性阻塞性肺疾病(COPD)患者执行功能障碍的危险因素,为提高COPD患者执行功能采取应对措施提供可靠的基础依据。方法选取2015年9月至2016年8月在华北理工大学附属医院呼吸内科确诊COPD的301名患者为研究对象。采用执行功能缺陷综合征的行为学评价测试(BADS)进行评测,根据评测结果将COPD患者确定为病例组和对照组。严格按照纳入排除标准,将BADS总标准分≤9分者纳入执行功能障碍组(病例组),共179人;将BADS总标准分9分者纳入执行功能非障碍组(对照组),共122人。通过问卷形式,对患者的一般人口学资料、工作情况、生活方式、睡眠情况、心理社会因素及疾病特征等相关因素进行调查和收集,应用SPSS17.0统计软件包,采用卡方检验和Logistic回归对数据进行统计分析,探讨COPD患者执行功能障碍的危险因素。结果1影响COPD患者执行功能障碍的单因素分析结果显示,COPD患者的年龄、婚姻状况、文化程度、居住地、工作与否、工作性质、吸烟情况、阅读情况、关注新闻情况、有无业余爱好、体育锻炼、参与社区活动、食用腌制品情况、使用铝制锅具情况、睡眠状况、抑郁程度、家庭支持情况、患病时间、自发病后复发次数、伴随其他疾病种类、疾病症状种类数、FEV1/FVC、肺功能分级、Sp O2与执行功能障碍的发生有关,差异有统计学意义(P0.05)。2影响COPD患者执行功能障碍的多因素分析多因素Logistic回归分析结果显示,年龄、婚姻状况、业余爱好、使用铝制锅具、睡眠质量、FEV1/FVC、肺功能分级、Sp O2是COPD患者执行功能障碍的影响因素,差异有统计学意义(P0.05)。OR值由大到小依次是FEV1/FVC重度下降(OR=43.916)、肺功能重度损伤(OR=13.346)、无业余爱好(OR=9.061)、Sp O294%(OR=8.967)、无配偶(OR=6.928)、使用铝制锅具3次/周(OR=5.349)、年龄(OR=4.528)、睡眠障碍(OR=3.589)。结论COPD患者的年龄≥70岁、无配偶、无业余爱好、使用铝制锅具、睡眠障碍、FEV1/FVC重度下降、肺功能重度损伤、Sp O294%是发生执行功能障碍的危险因素。
[Abstract]:Objective To analyze the risk factors of functional dysfunction in patients with chronic obstructive pulmonary disease (COPD) and to provide a reliable basis for improving the performance of patients with chronic obstructive pulmonary disease (COPD). Methods 301 patients with COPD were selected from September 2015 to August 2016 at the Affiliated Hospital of North China University of Technology. The behavior evaluation test (BADS) for performing functional defect syndrome was used to evaluate the patients with COPD as the case group and the control group according to the evaluation results. In strict accordance with the inclusion exclusion criteria, the BADS total standard score of 9 was included in the executive dysfunction group (case group) and 179; the BADS total score of 9 was included in the executive function non-barrier group (control group), with a total of 122. In the form of questionnaire, the data of general demographic data, working condition, life style, sleep condition, psychosocial factors and disease characteristics of the patient were investigated and collected, and the data were analyzed by Chi-square test and logistic regression using the SPSS 10.0 statistical software package. Objective To study the risk factors of functional dysfunction in patients with chronic obstructive pulmonary disease (COPD). Results 1 The single factor analysis of the performance dysfunction in COPD patients showed that the age, the marital status, the degree of culture, the place of residence, the work, the nature of the work, the smoking status, the reading situation, the information about the news, the existence of the hobby and the physical exercise of the COPD patients. participating in community activities, eating the marinade, using the aluminum pan, the sleeping condition, the degree of depression, the family support, the time of the illness, the number of times of recurrence since the onset of the disease, the type of other disease, the number of disease symptoms, the FEV1/ FVC, the lung function classification, The results of multi-factor logistic regression analysis of the multi-factor analysis of functional dysfunction in patients with COPD showed that age, marital status, hobbies, use of aluminum cookware, sleep quality, FEV1/ FVC, pulmonary function classification, The difference was statistically significant (P0.05). The OR value was from large to small, with a severe decrease in FEV1/ FVC (OR = 43.916), severe lung function (OR = 13.346), no hobby (OR = 9.061), Sp O294% (OR = 8.967), no spouse (OR = 6.928), and 3 times/ week for aluminum (OR = 5.349). Age (OR = 4.528), sleep disorder (OR = 3.589). Conclusion The age of COPD patients is 70 years old, no spouse, no hobby, use of aluminum pan, sleep disorder, FEV1/ FVC severe decline, lung function severe injury, Sp O294% is the risk factor to carry out dysfunction.
【学位授予单位】:华北理工大学
【学位级别】:硕士
【学位授予年份】:2017
【分类号】:R473.5

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