血培养与PCT联合检测在脓毒血症早期诊断中的价值

发布时间：2019-06-27 11:10

【摘要】：目的探讨血培养与PCT联合检测在脓毒血症早期诊断中的价值。方法采用回顾性研究,从2015年3月到2016年3月,选择我院45例脓毒血症患者作为观察组,选取一般感染者45例作为对照组。采集所有研究对象静脉血液进行培养和PCT、CRP含量测定。结果观察组APACHE-II评分、CRP、PCT和血培养阳性率显著高于对照组,差异有统计学意义(P0.05)。但两组平均动脉压,WBC计数异常差异无统计学意义(P0.05)。观察组中脓毒血症患者26例,脓毒血症合并MODS13例,脓毒性休克6例。三组PCT水平比较有统计学差异(P0.05)。根据住院后第7d患者结果分为死亡组11例,好转组34例,死亡组住院第1d血浆PCT值显著高于好转组,随后好转组患者血浆PCT显著降低,死亡组血浆PCT显著升高,差异均有统计学意义(P0.05)。结论血浆PCT的值与脓毒血症患者的病情呈正相关,血培养和PCT联合检测对于脓毒血症的早期诊断和预后判断具有重要临床价值。
[Abstract]:Objective to evaluate the value of combined detection of blood culture and PCT in the early diagnosis of sepsis. Methods from March 2015 to March 2016, 45 patients with sepsis in our hospital were selected as observation group and 45 patients with general infection as control group. Venous blood was collected from all subjects for culture and PCT,CRP content determination. Results the positive rate of APACHE-II score, CRP,PCT and blood culture in the observation group was significantly higher than that in the control group (P 0.05). However, there was no significant difference in mean arterial pressure and WBC count between the two groups (P 0.05). In the observation group, there were 26 patients with sepsis, 13 patients with sepsis complicated with MODS and 6 patients with septic shock. There was significant difference in PCT level among the three groups (P 0.05). According to the results of the 7th day after hospitalization, the patients were divided into death group (n = 11) and improvement group (n = 34). The plasma PCT level in the death group was significantly higher than that in the improvement group on the first day of hospitalization, and the plasma PCT in the improvement group was significantly lower than that in the improvement group, and the plasma PCT in the death group was significantly increased (P 0.05). Conclusion the value of plasma PCT is positively correlated with the condition of sepsis patients. The combined detection of blood culture and PCT has important clinical value in the early diagnosis and prognosis of sepsis.
【作者单位】：濮阳市油田总医院检验科;
【分类号】：R459.7

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