过敏性休克和猝死的法医病理学诊断研究

发布时间：2019-08-26 09:39

【摘要】：目的:总结分析过敏性休克和猝死的法医病理学诊断,进而为法医学鉴定提供参考。方法:本次研究以2013年2月到2015年8月期间接收的10例过敏性休克和猝死患者为观察组,同时选取10例正常人员作为对照组1、10例非过敏性休克和猝死患者为对照组2,所有人员采用荧光酶联免疫法(FEIA)、酶联免疫吸附法(FLISA)以及免疫组织化学方法测定不同组人员中的相关指标,比较分析不同组人员在相关指标上的差异性。结果:在血清类胰蛋白酶含量以及血清Ig E方面,观察组和对照组1之间存在着明显差异(P0.05),具有统计学意义;在咽喉、肺部、胃组织的胰蛋白酶含量以及P物质的PI值方面,观察组和对照组2之间存在着明显差异(P0.05),具有统计学意义。结论:过敏性休克以及猝死患者的胰蛋白酶含量高于正常人群,同时在咽喉、胃组织以及肺部的P物质PI值方面,过敏性猝死高于非过敏性猝死人员,因而,对于怀疑为过敏性休克以及猝死人员,可根据实际情况通过血清Ig E、胰蛋白酶含量以及P物质的PI值等指标综合性的对过敏性休克和猝死人员作出诊断。
[Abstract]:Objective: to summarize and analyze the forensic pathological diagnosis of anaphylactic shock and sudden death, and to provide reference for forensic identification. Methods: ten patients with anaphylactic shock and sudden death received from February 2013 to August 2015 were selected as observation group, 10 normal persons as control group 1 and 10 patients with non-anaphylactic shock and sudden death as control group 2. All patients were determined by fluorescence enzyme-linked immunosorbent assay (FEIA),) enzyme-linked immunosorbent assay (Elisa) and immunohistochemical method. The differences of related indexes in different groups were compared and analyzed. Results: there were significant differences in serum trypsin content and serum Ig E between the observation group and the control group 1 (P 0.05), and there were significant differences in the trypsin content in throat, lung and stomach and the Pi value of substance P between the observation group and the control group 2 (P 0.05). Conclusion: the content of trypsin in patients with anaphylactic shock and sudden death is higher than that in normal people. At the same time, sudden anaphylactic death is higher than that in non-anaphylactic sudden death in terms of Pi value of substance P in throat, stomach tissue and lungs. Therefore, for suspected anaphylactic shock and sudden death, serum Ig E can be used according to the actual situation. Trypsin content and Pi value of substance P were used to diagnose anaphylactic shock and sudden death.
【作者单位】：山西省蒲县公安局刑警大队技术中队;
【分类号】：D919.4

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