鲫鱼对水中有机防晒剂的富集及代谢酶响应
发布时间:2017-12-28 16:08
本文关键词:鲫鱼对水中有机防晒剂的富集及代谢酶响应 出处:《中国环境科学》2017年09期 论文类型:期刊论文
更多相关文章: 鲫鱼 OD-PABA 组织分布 生物富集 代谢酶
【摘要】:采用半静态水体暴露方法研究了有机防晒剂对二甲氨基苯甲酸异辛酯(OD-PABA)在鲫鱼不同组织的分布、累积及生态毒理效应.结果表明,OD-PABA在不同组织中的含量随着水体暴露浓度的升高而持续升高,并在14或28d达到最大.不同浓度的OD-PABA在不同组织的生物富集因子(BCF)存在明显差异,基于暴露14d和28d计算得到的BCF值,肝脏为123~186,皮肤为117~163,肾脏为90.2~147.OD-PABA对鲫鱼肝脏EROD、PROD、BFCOD和GST活性都产生了诱导效应,其中EROD和GST的响应更为显著,最大诱导倍数分别为0.97和0.53倍.结果表明,水中的OD-PABA可在鲫鱼体内富集,并通过I相和II相代谢酶进行生物转化.
[Abstract]:The semi static water of organic sunscreen to two methyl amino benzoic acid isooctyl ester (OD-PABA) method to expose the distribution, accumulation and ecotoxicological effects in different tissues of crucian carp. The results showed that the content of OD-PABA in different tissues increased with the exposure concentration and water continued to rise, and reached a maximum at 14 or 28d. The concentration of OD-PABA in different tissues of the enrichment of biological factors (BCF) have obvious difference, the exposure of 14d and 28d were calculated based on the BCF value, liver 123~186, skin 117~163, kidney 90.2~147.OD-PABA on EROD, PROD and BFCOD in liver of crucian carp and GST activity induced effect, the response of EROD and GST more obviously, the maximum induction times were 0.97 and 0.53 times. The results show that the water OD-PABA in crucian carp enrichment, and through the I phase and II phase metabolic enzyme biological transformation.
【作者单位】: 西藏农牧学院水利土木工程学院;河海大学环境学院浅水湖泊综合治理与资源开发教育部重点实验室;
【基金】:西藏农牧学院雅江学者计划(2015XYA01) 国家自然科学基金创新群体项目(51769034)
【分类号】:X592
【正文快照】: 有机防晒剂(Organic UV Filters,OUVFs)是具有羰基共轭或杂环的芳香族有机化学品,具有强烈地选择性吸收紫外线的性能.OUVFs除了作为防晒成分用于个人护理品以外,还被广泛添加到家居产品、纺织品、塑料、光学产品、农业化学品和涂料等产品中,防止紫外线照射[1].近年来,紫外线辐,
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