合成麝香的研究新进展与当前挑战:从人体护理、环境污染到人体健康

发布时间：2018-04-21 14:49

本文选题：合成麝香 + 迁移转化过程　；参考：《化学进展》2017年09期

【摘要】：合成麝香(Synthetic Musks,SMs)因具有类似天然麝香的芬芳气味,被广泛添加于各种日化产品中。由于这类化合物的大量使用以及我国现有污水处理系统的局限性,目前在各种环境介质、人体内频繁检出SMs,从某种意义上来说该类化合物已经对生态环境和人类健康造成了一定潜在危害,因此是一类重要的新兴有机污染物。本文详细综述了SMs的环境污染水平、迁移转化机制、环境归趋、环境危害以及健康效应等方面的最新研究进展;发现虽然这类污染物在环境转化过程中存在毒性增强等潜在的危害,但其在环境与生物体内的迁移转化机制尚未明确,且相关代谢转化产物的毒性效应研究并不多见,尤其在SMs暴露模式与人体损伤机制之间的相互关系研究方面还存在空白。此外,新型SMs如大环麝香与脂环麝香的健康效应的研究也有待进一步加强。
[Abstract]:Synthetic Musks synthetic musks (SMs) has been widely used in various daily chemical products because of its natural musk aroma. Due to the extensive use of these compounds and the limitations of the existing sewage treatment systems in our country, they are currently in various environmental media, SMs are frequently detected in human body. In a sense, these compounds have caused some potential harm to the ecological environment and human health, so they are a kind of important new organic pollutants. In this paper, the latest research progress in environmental pollution level, migration and transformation mechanism, environmental fate, environmental hazards and health effects of SMs are reviewed in detail. It was found that although such pollutants had potential hazards such as enhanced toxicity in the process of environmental transformation, the mechanisms of their migration and transformation in the environment and organisms were not clear, and the toxic effects of the related metabolites were rarely studied. In particular, there are gaps in the study of the relationship between SMs exposure patterns and human injury mechanisms. In addition, the health effects of novel SMs such as macrocyclic musk and lipopyclic musk need to be further strengthened.
【作者单位】：广东工业大学环境健康与污染控制研究院环境科学与工程学院广州市环境催化和污染控制重点实验室;
【基金】：国家自然科学基金项目(No.41425015,41603115,41573086) 广东省自然科学基金项目(No.2016A030310120)资助~~
【分类号】：TQ655;X503.1

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