脊髓背角胶状质神经元形态与电生理学特性的研究进展

发布时间：2018-01-07 18:32

本文关键词：脊髓背角胶状质神经元形态与电生理学特性的研究进展　出处：《生理科学进展》2016年06期 　论文类型：期刊论文

【摘要】：脊髓背角胶状质神经元在痛信息传递过程中具有重要作用。其形态学分类及电生理学特性复杂,形态学大体上可分为岛神经元、中央神经元、放射状神经元、垂直神经元以及不能分类神经元;电生理学主要包括被动膜特性(静息电位、膜电容和膜电阻)、主动膜特性(动作电位,包括其放电模式、阈值、基电流、半宽度、振幅等)以及兴奋性或抑制性突触后电流等。本文对国内外脊髓背角胶状质神经元形态学与电生理学的研究进展予以综述。
[Abstract]:The colloidal neurons in the dorsal horn of spinal cord play an important role in the transmission of pain information. Their morphological classification and electrophysiological characteristics are complex, which can be divided into island neurons, central neurons and radial neurons. Vertical neurons and unclassified neurons; Electrophysiology mainly includes passive membrane characteristics (resting potential, membrane capacitance and membrane resistance), active membrane characteristics (action potential, including its discharge mode, threshold, base current, half width). ) and excitatory or suppressive postsynaptic currents. In this review, the morphological and electrophysiological studies of colloidal neurons in the dorsal horn of the spinal cord at home and abroad are reviewed.
【作者单位】：南昌大学第一附属医院儿科;
【基金】：国家自然科学基金(81260175;81560198)资助课题
【分类号】：R338
【正文快照】： 脊髓背角胶状质(substantia gelatinosa,SG)区,即脊髓背角II层,是外周伤害性信息向中枢传递的第一个中继站。伤害性信息经由Aδ及C纤维传入,在SG区得到初步整合,再经过脊髓丘脑束等上行通路进入中枢神经系统高级部位,同时SG区还汇聚来自脑干和大脑皮质的下行抑制性投射神经纤

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