两种利用micro-CT测量小鼠牙周炎模型牙槽骨吸收的方法比较

发布时间：2018-01-10 14:05

本文关键词：两种利用micro-CT测量小鼠牙周炎模型牙槽骨吸收的方法比较　出处：《中国介入影像与治疗学》2017年03期 　论文类型：期刊论文

【摘要】：目的比较两种利用微计算机断层扫描(micro-CT)测量小鼠牙周炎模型牙槽骨吸收的方法。方法结扎小鼠右侧上颌第二磨牙建立牙周炎模型,分离其右侧上颌骨后进行micro-CT扫描。由3名医师分别采用重建法(R法)和改良的断层测量法(T法)进行牙槽骨测量,分析比较两种测量方法的一致性和稳定性。结果不同测量者采用R法进行测量的标准差(SD)为35.67μm,采用T法的SD为14.24μm,差异有统计学意义(P0.05);同一测量者采用R法测量3次所得结果之间的SD为34.87μm,采用T法的SD为7.82μm,差异有统计学意义(P0.05)。结论采用T法测量小鼠牙周炎模型牙槽骨吸收的一致性和稳定性均优于R法。
[Abstract]:Objective to compare two methods of measuring alveolar bone resorption in mouse periodontitis model by micro-CTM. Methods the periodontitis model was established by ligating the right maxillary second molar of mice. The right maxillary bone was separated and scanned by micro-CT. The alveolar bone was measured by the reconstruction method (R method) and the modified tomography method (T method). Results the standard deviation (SD) of R method and T method were 35.67 渭 m and 14.24 渭 m, respectively. The difference was statistically significant (P 0.05). The SD between the three times measured by R method and T method was 34.87 渭 m and 7.82 渭 m, respectively. Conclusion the consistency and stability of alveolar bone resorption measured by T method is better than that of R method.
【作者单位】：南京大学医学院附属口腔医院牙周科;南京大学医学院附属口腔医院牙体牙髓科;南京大学医学院附属口腔医院口腔种植科;
【基金】：国家自然科学基金(81570982;81371152) 江苏省双创计划引进人才[苏人才办(2014)27] 江苏特聘医学专家资助项目[苏卫人(2014)49号]
【分类号】：R781.4;R-332
【正文快照】： 图1　测量方法　A.测量位点;B.以R法测量各位点的CEJ-ABC;C.CT示小鼠上颌骨的冠状位(红色)、轴位(绿色)、矢状位(蓝色);D.小鼠牙体长轴与y轴(红线)平行;E.牙合面近远中长轴与x轴(蓝线)平行;F.牙合面与z轴(绿线)平行;G.于冠状位测量某一位点的CEJ-ABC(两平行黄线之间的垂直距离

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