隐孢子虫实验室安全风险评估模型的建立

发布时间：2018-01-22 04:54

本文关键词： 隐孢子虫实验室安全模糊层次分析法多指标综合评分法　出处：《中国血吸虫病防治杂志》2016年06期 　论文类型：期刊论文

【摘要】：目的建立隐孢子虫实验室安全风险评估模型,为从事隐孢子虫相关操作的实验室人员做好安全工作和预防实验室内发生隐孢子虫感染提供依据。方法通过查阅文献和德尔菲法确定隐孢子虫实验室感染发生的风险因素,然后通过模糊层次分析法确定风险因素的权重,建立隐孢子虫实验室安全风险评估模型。结果建立了隐孢子虫实验室安全风险评估模型,各风险指标中粪便样本处理发生隐孢子虫实验室感染的概率较高,且危害程度高,其发生可能性、危害程度的指标组合权重分别为0.111和0.107,属于高危风险因素。结论本研究建立的隐孢子虫实验室安全风险评估模型具有可行性,可望为实验室人员做好相应防护措施、预防实验室内发生隐孢子虫感染发生提供依据。
[Abstract]:Objective to establish a laboratory safety risk assessment model for Cryptosporidium. To provide a basis for the safety work and prevention of Cryptosporidium infection among laboratory personnel engaged in cryptosporidium related operations. Methods the incidence of Cryptosporidium infection in laboratory was determined by literature review and Delphi method. Risk factors. Then the weight of risk factors is determined by fuzzy analytic hierarchy process (AHP) and the model of laboratory safety risk assessment of Cryptosporidium is established. Results the model of laboratory safety risk assessment of Cryptosporidium is established. Among the risk indicators, the probability of laboratory infection of Cryptosporidium in fecal sample treatment was higher, and the degree of harm was high. The probability of occurrence and the combined weight of the index of hazard degree were 0.111 and 0.107, respectively. Conclusion the model of laboratory safety risk assessment of Cryptosporidium is feasible, and it is expected to be a good protective measure for laboratory personnel. To prevent Cryptosporidium infection in laboratory.
【作者单位】：中国疾病预防控制中心寄生虫病预防控制所、世界卫生组织热带病合作中心、卫生部寄生虫病原与媒介生物学重点实验室;上海市嘉定区疾病预防控制中心;
【基金】：上海市卫生和计划生育委员会委级课题(20134430)
【分类号】：R382.3
【正文快照】： 隐孢子虫病是一种以腹泻为主要临床表现的人兽共患原虫病[1]。作为隐孢子虫病的病原,隐孢子虫主要寄生于人或其他动物肠上皮细胞的刷状缘层,亦可寄生于呼吸道、肺、扁桃体、胰腺、胆囊和胆管等器官[1]。隐孢子虫的感染阶段为卵囊,其呈圆形或椭圆形,直径4~6 mm,并随宿主粪便或

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